PERSANTIN 75mg Price

Overview

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This medicine contains an important and useful components, as it consists of
Dipyridamoleis available in the market in concentration

Name

Dipyridamole

Precaution

In patients with rapidly worsening angina, subvalvular aortic stenosis, haemodynamic instability associated with recent MI or coagulation disorders esp when given IV during myocardial imaging. Hypotension, unstable angina, aortic stenosis. Pregnancy and lactation. Safety and efficacy are not established in childn < 12 yrs. Lactation: enters breast milk; use with caution

Indication

Stroke, Thromboembolism, Transient ischaemic attack

Contra indication

Hypersensitivity. Peptic ulcer.

Side Effect

>10% Chest pain (20%),Abnormal ECG (15.9%),Dizziness (12%) 1-10% ST-T changes (7.5%),Abdominal discomfort, oral (6.1%),Extrasystole (5%),Flushing (3.4%),Generalized pain (2.6%),Headache, oral (2.3%) Frequency Not Defined Myocardial infarction (rare),Ventricular arrhythmia (rare),Bronchospasm (rare),Dyspnea

Pregnancy Category ID

2

Mode of Action

Dipyridamole causes an accumulation of adenosine, adenine nucleotides and cAMP by inhibiting the activity of adenosine deaminase and phosphodiesterase thus inhibiting platelet aggregation and may cause vasodilation.

Interaction

Aminophylline may reverse vasodilatation effect. Useful combination with aspirin in prevention of thromboembolism. Efficacy reduced by concurrent admin of antacids. Concurrent use may increase the cardiotoxic effects of adenosine. Potentially Fatal: Potentiates effects of oral anticoagulants and antiarrhythmic agents.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration