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ALOXI Price

Active Substance: Palonosetron (as HCl).

459
UAD , based on 7541 reviews.
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Overview

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This medicine contains an important and useful components, as it consists of
Palonosetron (as HCl)is available in the market in concentration

Name

Palonosetron

Precaution

Patients with intestinal obstruction or ileus. Rapid inj may lead to temporary visual changes e.g. blurred vision. Patients who have or may develop prolonged QT intervals. Safety and efficacy not established in children <18 yr. Counsel patients who handle skilled tasks e.g. driving may be impaired. Lactation: unknown, discontinue drug or do not nurse

Indication

Chemotherapy-induced nausea and vomiting, Postoperative nausea and vomiting

Contra indication

History of hypersensitivity.

Side Effect

1-10% Prolonged QT interval (up to 5% ),Anxiety,Dizziness,Headache,Weakness,Constipation,Diarrhea,Prutitus,Hyperkalemia,LFT's increased <1% First degree atrioventricular block,Second degree atrioventricular block Frequency Not Defined Immune hypersensitivity reaction (very rare),Seizure

Pregnancy Category ID

2

Mode of Action

Palonosetron is a selective 5-HT3 antagonist that is used in the prevention of acute and delayed emesis in emetogenic cancer chemotherapy regimens.

Interaction

May have additive effect on prolonging QT with drugs e.g. moxifloxacin, erythromycin, antipsychotics and TCAs.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration

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