ALKERAN 2mg Price

Overview

Welcome to Dwaey, specifically on ALKERAN 2mg Tablets page.
This medicine contains an important and useful components, as it consists of Melphalan.
ALKERAN 2mg is available in the market in concentration 2mg/Tablet and in the form of Tablets.

GLAXO WELLCOME GmbH & CO. KG is the producer of ALKERAN 2mg and it is imported from GERMANY, The most popular alternatives of ALKERAN 2mg are listed downward .

Mode Of Action

Melphalan, a mechlorethamine derivative, is an alkylating antineoplastic agent. It forms carbonium ions, resulting in DNA and RNA synthesis inhibition. It cross-links DNA strands and acts on both resting and rapidly dividing tumour cells.

Indication

• Breast cancer
• Ovarian cancer
• Multiple myeloma
• Neuroblastoma
• Soft tissue sarcoma
• Malignant melanoma
• Retinoblastoma
• Polycythaemia vera

Precaution

Renal impairment. Lactation. Prior bone marrow suppression, prior chemotherapy or irradiation. May mask signs of infection e.g. fever and increased WBC. Elderly. Lactation: not known if excreted in breast milk

Side Effects

• >10% Myelosuppression (30%) Frequency Not Defined Diarrhoea
• stomatitis
• vomiting; haemolytic anaemia
• vasculitis
• pulmonary fibrosis
• hepatic disorders
• suppression of ovarian function in premenopausal women
• temporary or permanent sterility in male patients. Allergic reactions. Potentially Fatal: Bone marrow suppression. Secondary malignancy
• cardiac arrest. Anaphylaxis.

Contra indication

Hypersensitivity. Severe bone marrow suppression. Pregnancy.

Pregnancy and lactation

Pregnancy category: D

There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.