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ORATANE 30 mg Price

Active Substance: Isotretinoin.

225
UAD , based on 7541 reviews.
View Drug details

Overview

Welcome to Dwaey, specifically on ORATANE 30 mg Capsules (Soft Gelatin) page.
This medicine contains an important and useful components, as it consists of Isotretinoin.
ORATANE 30 mg is available in the market in concentration 30 mg/ Capsule and in the form of Capsules (Soft Gelatin).

DOUGLAS PHARMACEUTICALS LIMITED is the producer of ORATANE 30 mg and it is imported from NEW ZEALAND, The most popular alternatives of ORATANE 30 mg are listed downward .

Mode Of Action

Isotretinoin is a synthetic retinoid which reduces sebaceous gland size and sebum production. It also regulates cell proliferation and differentiation.

Indication

  • Acne

Precaution

Preexisting or predisposition to hypertriglyceridaemia (e.g. DM, obesity or increased alcohol intake). Monitor triglyceride levels. Monitor blood lipids and LFTs at wkly or bi-wkly intervals. Monitor blood glucose in known or suspected DM patients. Genetic predisposition for age-related osteoporosis, history of childhood osteoporosis, osteomalacia or other bone metabolism disorders. Anorexia nervosa. History of psychiatric disorder. May impair night vision. Avoid wax epilation and skin resurfacing procedures for at least 6 mth. Avoid prolonged exposure to UV light or sunlight. Discontinue if hearing impairment, abdominal pain, rectal bleeding, severe diarrhoea or adverse ocular effects occur. Patient should not donate blood during therapy and for at least 1 mth following drug discontinuation. Lactation: Unknown whether distributed into breast milk; because of potential for serious adverse reactions in nursing infants, do not administer to women who are breastfeeding

Side Effects

  • >10% Cheilitis (90%)
  • Xerosis
  • Xerostomia
  • Dry nose
  • Epistaxis
  • Pruritus
  • Conjunctivitis (including blepharoconjunctivitis) (40%)
  • Irritation (40%)
  • Increased erythrocyte sedimentation rates (40%)
  • Thinning of hair (which has persisted in rare instances)
  • Palmoplantar desquamation
  • Skin fragility
  • Skin infections (eg
  • paronychial infections)
  • Rash (including erythema
  • seborrhea
  • eczema)
  • photosensitivity
  • Hypertriglyceridemia (25%)
  • Bone or joint pain
  • Generalized muscle aches
  • Arthralgia
  • Decreased HDLs (15%)
  • Increased LFTs (15%)
  • Increased CPK (12-24%)
  • Decreased hemoglobin concentration and hematocrit
  • Decreased erythrocyte and leukocyte counts
  • Increased platelet count 1-10% Decreased bone mineral density (8.8%)
  • Premature epiphyseal closure (3%) Frequency Not Defined Lethargy
  • Fatigue
  • Headache
  • Anorexia
  • Nausea
  • Vomiting
  • Increased appetite
  • Thirst Potentially Fatal: Anaphylaxis. Haemorrhagic pancreatitis.

Contra indication

Pregnancy, lactation.

Pregnancy and lactation

Pregnancy category: X

Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Interaction

Additive toxicity with vitamin A or its derivatives. Decreased efficacy of microdosed progesterone (use 2 forms of contraception). May increase risk of bone loss with phenytoin. May increase risk of osteoporosis with systemic corticosteroids. Reduces plasma levels of carbamazepine. Potentially Fatal: Increased risk of pseudotumor cerebri with tetracyclines.

Alternatives Price List

  • TRETIN 20UAD 181
  • TRETIN 10UAD 104
  • TRETIN 0.05% UAD 22
  • SOTRET 20mgUAD 100
  • SOTRET 10mgUAD 40

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