Active Substance: Dutasteride.
Overview
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This medicine contains an important and useful components, as it consists of
Dutasterideis available in the market in concentration
Dutasteride
Excreted in semen therefore use of condom is recommended. Women of childbearing potential should avoid handling dutasteride capsules. Advisable to exclude other causes of benign prostatic hypertrophy (e.g. prostate cancer, infection) before initiating therapy. Lactation: Excretion in milk unknown/contraindicated
Benign prostatic hyperplasia (BPH)
Severe liver impairment; pregnant women, children, adolescent.
1-10% Impotence,Decreased libido,Ejaculation disorder,Breast disorders/gynecomastia <1% Dizziness Frequency Not Defined Cardiac failure,Prostate cancer (high grade)
5
Dutasteride has antiandrogenic properties. It inhibits 5alpha-reductase, thus preventing the conversion of testosterone to 5?-dihydrotestosterone which is the main androgen involved in causing prostate enlargement.
Plasma concentrations may be increased when used concomitantly w/ moderate or potent CYP3A4 inhibitors.
Information not available