NOVONORM 1mg price in UAE

Overview

Welcome to Dwaey, specifically on NOVONORM 1mg Tablets page.
This medicine contains an important and useful components, as it consists of Repaglinide.
NOVONORM 1mg is available in the market in concentration 1mg/Tablet and in the form of Tablets.

NOVO NORDISK A/S is the producer of NOVONORM 1mg and it is imported from DENMARK, The most popular alternatives of NOVONORM 1mg are listed downward .

Mode Of Action

Repaglinide stimulates release of insulin from pancreatic beta-cells by inhibiting K efflux via closure of ATP regulated K channels. This results in depolarization of the cell and opening of voltage-dependent Ca channels, which increases influx of Ca into the beta cells and causes release of insulin.

Indication

Type 2 DM

Precaution

Myocardial infarction, coma, trauma during surgery, elderly, malnourished and debilitated patients. Hepatic or severe renal impairment. Pregnancy.

Side Effects

Hypoglycaemia
nausea
diarrhoea
constipation
vomiting
dyspepsia
arthralgia
sinusitis
rhinitis
back pain; rash
pruritus
urticaria; visual disturbances.

Contra indication

Diabetic ketoacidosis; severe hepatic impairment, type 1 diabetes; hypersensitivity. Lactation.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Cytochrome P450 3A4 inducers eg. rifampicin, barbiturates and carbamazepine may increase repaglinide metabolism. NSAIDs and other highly protein bound drugs eg, salicylates, sulphonamides, phenylbutazone, oral anticoagulants and hydantoins may potentiate action of repaglinide. Ketoconazole, fluconazole, itraconazole and erythromycin may increase plasma conc of repaglinide. Antagonistic effect with drugs causing hyperglycaemia. Concurrent use with gemfibrozil may lead to enhanced and prolonged blood glucose lowering effect. Potentially Fatal: Increased risk of myocardial infarction when used with isophane insulin.