NORADRENALIN SINTETICA 4mg/4ml Price

Overview

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This medicine contains an important and useful components, as it consists of
Noradrenaline (as tartrate)is available in the market in concentration

Name

Norepinephrine (Noradrenaline)

Precaution

Not a substitute for replacement of blood, plasma, fluids, and/or electrolytes; correct volume depletion prior to admin. Identify and correct hypoxia, hypercapnia and acidosis prior to or during admin. Avoid extravasation as tissue necrosis may occur. Avoid inj into leg veins, especially in elderly or those with occlusive vascular diseases, arteriosclerosis, DM or Buerger's disease. Hypertensive or hyperthyroid patients. In conjunction with local anaesthetics, do not use in fingers, toes, ears, nose or genitalia. Lactation. Lactation: Not known if excreted into breast milk; avoid use during breastfeeding

Indication

Acute Hypotension, Cardiac Arrest, Sepsis & Septic Shock

Contra indication

Hypersensitivity. Hypertension. Pregnancy. Patients with peripheral or mesenteric vascular thrombosis unless necessary as a life-saving procedure. Concomitant use with some general anesthetics: Chloroform, trichloroethylene, cyclopropane, halothane

Side Effect

Hypertension, headache, peripheral ischaemia, bradycardia, arrhythmias, anxiety, skin necrosis (with extravasation), dyspnoea, respiratory difficulty.

Pregnancy Category ID

3

Mode of Action

Norepinephrine is a direct-acting sympathomimetic which stimulates alpha 1- and beta-adrenergic receptors. Its alpha-agonist effects cause vasoconstriction, thereby raising systolic and diastolic BP with reflex slowing of heart rate.

Interaction

Guanethidine, methyldopa, reserpine, TCAs may increase pressor response to norepinephrine. Potentially Fatal: Increased risk of arrhythmias with cocaine, cyclopropane or halogenated hydrocarbon anaesthetics. Hypertensive crisis may occur with MAOIs. Hypertensive effects may be increased by nonselective ?-blockers.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration