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NEVOTIC Price

Active Substance: Levofloxacin.

39
UAD , based on 7541 reviews.
View Drug details

Overview

Welcome to Dwaey, specifically on NEVOTIC Tablets/Film-coated page.
This medicine contains an important and useful components, as it consists of Levofloxacin.
NEVOTIC is available in the market in concentration 500mg/Tablet and in the form of Tablets/Film-coated.

PHARMA INTERNATIONAL CO. is the producer of NEVOTIC and it is imported from JORDAN, The most popular alternatives of NEVOTIC are listed downward .

Mode Of Action

Levofloxacin exerts antibacterial action by inhibiting bacterial topoisomerase IV and DNA gyrase, the enzymes required for DNA replication, transcription repair and recombination. It has in vitro activity against a wide range of gram-negative and gram-positive microorganisms.

Indication

  • Chronic bronchitis
  • Acute bacterial sinusitis
  • Anthrax
  • Community-acquired pneumonia
  • Skin and skin structure infections
  • Nosocomial pneumonia
  • Urinary tract infections
  • Complicated skin and skin structure infections
  • Acute pyelonephritis
  • Chronic bacterial prostatitis

Precaution

Known or suspected CNS disorders (e.g. severe cerebral arteriosclerosis, epilepsy) or other risk factors that predispose to seizures. Avoid unnecessary exposure to sunlight or artificial UV light. History of prolonged QT interval, uncorrected electrolyte disturbances. DM (carefully monitor blood glucose levels). Periodically monitor renal, hepatic and haematopoietic functions during treatment. Pregnancy and lactation. Elderly. May impair ability to drive or operate machinery. Lactation: Drug excreted in breast milk; not recommended

Side Effects

  • 1-10% Nausea (7%)
  • Headache (6%)
  • Diarrhea (5%)
  • Insomnia (4%)
  • Constipation (3%)
  • Dizziness (3%)
  • Dyspepsia (2%)
  • Rash (2%)
  • Vomiting (2%)
  • Chest pain (1%)
  • Dyspnea (1%)
  • Edema (1%)
  • Fatigue (1%)
  • Injection-site reaction (1%)
  • Moniliasis (1%)
  • Pain (1%)
  • Pruritus (1%)
  • Vaginitis (1%) <1% Cardiac: Cardiac arrest
  • palpitation
  • ventricular tachycardia
  • arrhythmia Nervous system: Tremor
  • convulsions
  • paresthesia
  • vertigo
  • hypertonia
  • hyperkinesias
  • abnormal gait
  • somnolence
  • syncope Metabolic: Hypoglycemia
  • hyperglycemia
  • hyperkalemia Blood/lymphatic system: Anemia
  • thrombocytopenia
  • granulocytopenia Musculoskeletal/connective tissue: Arthralgia
  • tendonitis
  • myalgia
  • skeletal pain Gastrointestinal (GI): Gastritis
  • stomatitis
  • pancreatitis
  • esophagitis
  • gastroenteritis
  • glossitis
  • pseudomembranous/C difficile colitis Hepatobiliary: Abnormal hepatic function
  • increased hepatic enzymes
  • increased alkaline phosphatase Psychiatric: Anxiety
  • agitation
  • confusion
  • depression
  • hallucinations
  • nightmares
  • sleep disorder
  • anorexia
  • abnormal dreaming Other: Immune hypersensitivity reaction
  • acute renal failure
  • urticaria
  • phlebitis
  • epistaxis Potentially Fatal: Anaphylaxis.

Contra indication

Hypersensitivity to levofloxacin or other quinolones. Child <18 yr.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Additive effects on QT interval prolongation w/ class IA (e.g. quinidine, procainamide) or class III (amiodarone, sotalol) antiarrhythmics, fluoxetine or imipramine. Reduced absorption w/ sucralfate, didanosine, antacids containing Mg or Al, dietary supplements containing Zn, Ca, Mg or Fe. Altered glucose levels w/ antidiabetic agents (e.g. insulin, glibenclamide). Increased risk of severe tendon disorders w/ corticosteroids. Increased risk of CNS stimulation and seizures w/ NSAIDs. Increased prothrombin time w/ warfarin.

Alternatives Price List

  • VOXIN 500mg UAD 70
  • TAVANIC i.v. 500mgUAD 161
  • TAVANIC 500mgUAD 98
  • TAVANIC 500mgUAD 137
  • TAVANIC 250mgUAD 52

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