MONO-TILDIEM SR 200mg price in UAE

Overview

Welcome to Dwaey, specifically on MONO-TILDIEM SR 200mg Capsules (Hard Gelatin)/Sustained Release page.
This medicine contains an important and useful components, as it consists of Diltiazem HCl.
MONO-TILDIEM SR 200mg is available in the market in concentration 200mg/Capsule and in the form of Capsules (Hard Gelatin)/Sustained Release.

SANOFI WINTHROP INDUSTRIE is the producer of MONO-TILDIEM SR 200mg and it is imported from FRANCE, The most popular alternatives of MONO-TILDIEM SR 200mg are listed downward .

Mode Of Action

Diltiazem relaxes coronary vascular smooth muscles by inhibiting influx of calcium ions during depolarisation of the vascular smooth muscles and myocardium. It increases myocardial O2 delivery in patients with vasospastic angina and inhibits cardiac conduction, particularly at the SA and AV nodes.

Indication

Supraventricular tachycardia
Hypertension
Angina
Atrial fibrillation
Arrhythmias
Atrial flutter

Precaution

Elderly. Hepatic or renal impairment; impaired left ventricular function; prolonged AV periods; DM; hypotension. Avoid abrupt withdrawal and long-term use. Patients with sick-sinus syndrome, preexisting AV block, bradycardia and those taking beta-blockers or digitalis are at risk of developing AV block, bradycardia, asystole or sinus arrest. Lactation: Drug enters breast milk; because of risk for serious adverse reactions in nursing infants from diltiazem, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother

Side Effects

>10% Edema (2-15%)
Headache (5-12%) 1-10% Dizziness (3-10%)
AV block (2-8%)
Peripheral edema (2-8%)
Bradyarrhythmia (2-6%)
Headache (1-5%)
Hypotension (2-4%)
Nausea (3%)
Vomiting (2%)
Vasodilation (2-3%)
Extrasystoles (2%)
Flushing (1-2%)
Drug-induced gingival hyperplasia (<2%)
Myalgia (2%)
Diarrhea (1-2%)
Constipation (2-4%)
Bronchitis (1-4%)
Sinus congestion (1-2%)
Dyspnea (1-6%)
Congestion (1-2%) < 1% Increased Alkaline phosphatase as well as ALT and AST
CHF
Thrombocytopenia
Toxic epidermal necrolysis
Hemolytic anemia
Photosensitivity
Extrapyramidal symptoms
Syncope

Contra indication

Sick-sinus syndrome; 2nd or 3rd ° AV block; porphyria. Severe congestive cardiac failure; marked bradycardia. Pregnancy and lactation.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Increased AV blocking effect w/ clonidine. May increase serum levels of statins (e.g. atorvastatin, lovastatin), carbamazepine, phenytoin. May increase bradycardic affect of amiodarone, digoxin, mefloquine. May enhance antihypertensive effect w/ other antihypertensives (e.g. aldesleukin), antipsychotic. Increased serum levels w/ cimetidine. Decreased serum levels w/ rifampicin, phenobarbital. Potentially Fatal: IV: May enhance hypotensive effect of IV ?-blockers.