Active Substance: Hydrocortisone, Miconazole nitrate.
Overview
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This medicine contains an important and useful components, as it consists of
Hydrocortisone, Miconazole nitrateis available in the market in concentration
Hydrocortisone 1% + Miconazole Nitrate 2% Topical
For external use only; discontinue if sensitization or irritation occurs. It should be used with caution when applied to extensive surface areas or under occlusive dressings including baby napkins. Application to the face should be avoided.
Topical application to inflammatory skin condition where fungal infecton is present.
The drug is contraindicated in individuals with a history of sensitivity reactions to Miconazole or any of the components of the preparation, viral disease of the skin (herpes, chickenpox), perioral dermatitis, rosaceae, ulcerative conditions, tuberculous or syphilitic processes.
Generally it is well tolerated. An allergic reaction to any of the ingredient of the cream may occur. Rarely, irritation & burning may occur.
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Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency. Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients.
Oral anticoagulants eg, warfarin. Certain oral hypoglycemics & phenytoin. Hydrocortisone.
Information not available