MIKACIN 500mg/2ml I.M/I.V Price

Overview

Welcome to Dwaey, specifically on MIKACIN 500mg/2ml I.M/I.V page.
This medicine contains an important and useful components, as it consists of
Amikacin (as sulfate)is available in the market in concentration

Name

Amikacin

Precaution

Renal impairment; vertigo, tinnitus. Discontinue if signs of ototoxicity, neurotoxicity or hypersensitivity occurs; lactation. Safety has not been established for treatment period >14 days. Monitor renal function before and during treatment. Lactation: excretion in milk unknown/not recommended

Indication

Tuberculosis, Complicated and recurrent urinary tract infections, Severe Gram-negative infections, Non-tubercular mycobacterial infections, Bacterial septicemia, Infections of the respiratory tract, Bones and joints, Central nervous system and skin and soft tissue, Intra-abdominal infections, Burns, Postoperative infections, Meningitis, Peritonitis, Neonatal sepsis

Contra indication

Pregnancy, perforated ear drum, myasthenia gravis, hypersensitivity.

Side Effect

1-10% Neurotoxicity,Nephrotoxicity (if trough >10 mg/L),Ototoxicity <1% Hypotension,Headache,Drug fever,Rash,Nausea,Vomiting,Eosinophilia,Paresthesia,Tremor,Arthralgia,Weakness,Allergic reaction Potentially Fatal: Ototoxicity, nephrotoxicity, neuromuscular blockade.

Pregnancy Category ID

4

Mode of Action

Amikacin binds to 30S ribosomal subunits of susceptible bacteria, thus inhibiting its protein synthesis.

Interaction

Amphotericin B may lead to increased nephrotoxicity and reduced clearance of amikacin when used together. Potentially Fatal: Increased ototoxic or nephrotoxic effects with other nephrotoxic or ototoxic drugs. Enhanced neuromuscular blockade with neuromuscular blocking drugs. Increased risk of ototoxicity with potent diuretics.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration