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MACZIL10 Price

Active Substance: Donepezil HCl.

248
UAD , based on 7541 reviews.
View Drug details

Overview

Welcome to Dwaey, specifically on MACZIL10 Tablets/Film-coated page.
This medicine contains an important and useful components, as it consists of Donepezil HCl.
MACZIL10 is available in the market in concentration 10mg/Tablet and in the form of Tablets/Film-coated.

MACLEODS PHARMACEUTICALS LTD. is the producer of MACZIL10 and it is imported from INDIA, The most popular alternatives of MACZIL10 are listed downward .

Mode Of Action

Donepezil reversibly and noncompetitively inhibits centrally-active acetylcholinesterase. It is used for the symptomatic treatment of Alzheimer's disease.

Indication

  • Mild to moderately severe dementia in Alzheimer's disease.

Precaution

Caution when used in patients with sick sinus syndrome or cardiac conduction abnormalities. May increase secretion of gastric acid; caution when used in patients at risk of ulcer disease. Patients with COPD, asthma, history of epilepsy, bladder obstruction, prostatic hypertrophy. May cause dose-related diarrhoea, nausea and/or vomiting which usually resolves after 1-3 wk. Safety and efficacy have not been established in children. Pregnancy, lactation.

Side Effects

  • Nausea
  • vomiting
  • anorexia
  • wt loss
  • diarrhoea
  • insomnia
  • fatigue
  • muscle cramps; headache and dizziness; syncope
  • bradycardia; convulsions; increased liver transaminases; sinoatrial and atrioventricular block; hallucinations
  • agitation and aggressive behavior; minor increases in plasma creatine kinase; potentially bladder outflow obstruction.

Contra indication

Donepezil is contraindicated in patients with known hypersensitivity to donepezil hydrochloride or to piperidine derivatives.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

May increase the neurotoxic effect of antipsychotics. Concurrent use with systemic corticosteroids may increase the adverse effects of donepezil. May increase the neuromuscular-blocking effect of succinylcholine. May increase the adverse effects of cholinergic agonists. May increase the bradycardic effect of beta-blockers.

Alternatives Price List

  • MACZIL10 UAD 248
  • MACZIL 5 UAD 151
  • DOXERA 5UAD 227
  • DOXERA 10UAD 362
  • DOPZIL UAD 243

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