Active Substance: Lysate from Staphylococcus aureus, Streptococcus mitis, Streptococcus pyogenes, Streptococcus pneumonia, Klebsiella pneumonia, Branhamella catarrhalis and Haemophilus influenza (of at least 10^9 germs each).
Overview
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This medicine contains an important and useful components, as it consists of
Lysate from Staphylococcus aureus, Streptococcus mitis, Streptococcus pyogenes, Streptococcus pneumonia, Klebsiella pneumonia, Branhamella catarrhalis and Haemophilus influenza (of at least 10^9 germs each)is available in the market in concentration
Secnidazole
Avoid alcohol and disulfiram. Avoid in patients with history of blood disorders.
Giardiasis, Amoebiasis, Trichomoniasis
Hypersensitivity; pregnancy (1st trimester) and lactation.
Nausea, gastralgia, change of taste, metallic taste, stomatitis, urticaria, rashes, leucopenia. Rarely vertigo, moderate neurological, digestive disturbances.
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Secnidazole is active against E histolytica, G lamblia, T vaginalis, Clostridium spp, B fragilis, Gardnerella spp. The drug enters the microorganisms by diffusion and is reduced intracellularly by low oxidation-reduction potential ferredoxin which then result in DNA damage.
Concurrent disulfiram admin may cause psychotic reactions. Disulfiram-like reactions with alcohol. Cimetidine may prolong half-life. Potentially Fatal: May potentiate anticoagulant effect of warfarin and increase risk of haemorrhage.
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