Active Substance: Maprotiline HCl.
Overview
Welcome to Dwaey, specifically on LUDIOMIL 50mg page.
This medicine contains an important and useful components, as it consists of
Maprotiline HClis available in the market in concentration
Maprotiline Hydrochloride
Urinary retention, prostatic hyperplasia, chronic constipation, untreated angle-closure glaucoma; hyperthyroidism; risk of suicide; may precipitate mania or psychotic symptoms; withdraw gradually; may impair ability to operate machinery. Pregnancy and lactation; elderly. Lactation: avoid during breastfeeding
Depression
Preexisting CV insufficiency; epilepsy or lowered seizure threshold.
Common Fatigue,Sedation,Lethargy,Weakness,Constipation,Dry mouth,Blurred vision Less Common Agitation,Anxiety,Headache,Insomnia,Nausea,Vomiting,Sweating Infrequent Orthostatic hypotension, ECG changes, tachycardia Confusion, EPS, dizziness, paresthesia, tinnitus Rash,Incr LFTs,Sexual dysfunction Rare Seizure,Agranulocytosis,Thrombocytopenia,Eosinophilia,Leukopenia,SIADH Potentially Fatal: Seizures
2
Maprotiline is a tetracyclic antidepressant pharmacologically similar to the tricyclic antidepressants. It's antidepressant effects appear to be due principally to inhibition of the re-uptake of noradrenaline at the neuronal membrane.
MAOIs. Increase in sedative effect with alcohol. Increased effect of antidiabetics. Maprotiline concentrations and toxicity increased by propranolol, risperidone. Risk of seizures increased with phenothiazines.
Information not available