LOTRIDERM Price

Overview

Welcome to Dwaey, specifically on LOTRIDERM page.
This medicine contains an important and useful components, as it consists of
Betamethasone (as dipropionate), Clotrimazoleis available in the market in concentration

Name

Betamethasone 0.1% + Clotrimazole 1% Topical

Precaution

Systemic absorption of topical corticosteroids can produce reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency after withdrawal of treatment. Manifestations of Cushing's syndrome, hyperglycemia, and glucosuria can also be produced in some patients by systemic absorption of topical corticosteroids while on treatment. Conditions which augment systemic absorption include use over large surface areas, prolonged use, and use under occlusive dressings. If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent corticosteroid. Pediatric patients may be more susceptible to systemic toxicity from equivalent doses due to their larger skin surface to body mass ratios Lactation: Excretion in milk unknown; use with caution

Indication

Tinea pedis, tinea cruris, tinea corporis, ringworm, athlete's foot, jock itch.

Contra indication

Patients who are sensitive to clotrimazole, betamethasone dipropionate, other corticosteroids or imidazoles, or to any ingredient in these preparations.

Side Effect

1-10% Dry skin (2%),Paresthesia (2%),Local burning (2%) <1% Edema,Rash,Skin atrophy,Secondary infection,Skin ulceration,Acneiform eruption,Bruising,Folliculitis,Striae Clotrimazole Erythema,Stinging,Blistering,Peeling,Edema,Pruritus,Urticaria,General skin irritation Betamethasone Burning,Itching,Irritation,Dryness,Folliculitis,Hypertrichosis,Acneiform eruptions,Hypopigmentation,Perioral dermatitis,Allergic contact dermatitis,Skin maceration,Skin atrophy,Striae,Miliaria,HPA suppression (with higher potency used >2 wk)

Pregnancy Category ID

3

Mode of Action

Betamethasone is a corticosteroid with mainly glucocorticoid activity. It prevents and controls inflammation by controlling the rate of protein synthesis, depressing the migration of polymorphonuclear leukocytes and fibroblasts, and reversing capillary permeability and lysosomal stabilisation. Clotrimazole is an antifungal agent that binds to phospholipids in the fungal cell membrane. It causes loss of essential intracellular components by altering cell wall permeability.

Interaction

Information not available

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration