LORINASE-D price in UAE

Overview

Welcome to Dwaey, specifically on LORINASE-D Extended Release tablet page.
This medicine contains an important and useful components, as it consists of Desloratadine - Pseudoephedrine sulphate .
LORINASE-D is available in the market in concentration 2.5 mg/tablet - 120 mg/tablet and in the form of Extended Release tablet.

SPIMACO (AL QASSIM PHARMACEUTICAL PLANT) is the producer of LORINASE-D and it is imported from SAUDI ARABIA, The most popular alternatives of LORINASE-D are listed downward .

Mode Of Action

Desloratadine is a long-acting, tricyclic, non-sedating, selective peripheral histamine H1-receptor antagonist which inhibits the release of pro-inflammatory mediators from human mast cells and basophils. Pseudoephedrine is both an ?-and ?-adrenergic receptor agonist. It causes vasoconstriction via direct stimulation of ?-adrenergic receptors of the respiratory mucosa. It also directly stimulates ?-adrenergic receptors causing bronchial relaxation, increased heart rate and contractility.

Indication

Allergic rhinitis
Itching
Sneezing
Watery eyes
Runny nose
Hives
Skin rash
Common cold
Nasal congestion

Precaution

Severe renal or hepatic failure; children <6 mth, elderly, epilepsy, pregnancy and lactation. Lactation: both drugs pass into breast milk, pseudoephedrine is concentrated in breast milk; use caution

Side Effects

>10% Desloratadine Fever (12%)
Irritability (12%)
Headache (12%)
Diarrhea (15-21%)
Cough (11%)
Upper respiratory tract infection (11-21%) 1-10% Desloratadine Pharyngitis (4.1%)
Dry mouth (3%)
Myalgia (2.1%)
Emotional lability (3%)
Erythema (3%)
Macopapular rash (3%)
Dizziness (4%)
Fatigue (2.1%)
Somnolence (2.1%)Urinary tract infection (4%)
Dyspepsia (3%)
Insomnia (5%)
Dysmenorrhea (2.1%) Frequency Not Defined Pseudoephedrine CNS (tremor
restlessness
etc)
Insomnia
Arrhythmia
Hypotension
Tachycardia
Fatigue
Rash
Urticaria
Anorexia
Xerostomia
Dysuria
Polyuria
Nausea
Vomiting
Ischemic colitis

Contra indication

Hypersensitivity.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Potential increase in plasma concentrations w/ drugs affecting hepatic microsomal enzymes (e.g. azithromycin, cimetidine, erythromycin, fluoxetine, ketoconazole). Increased risk of hypertension and arrhythmias if given with cardiac glycosides, quinidine or TCAs. Increased risk of vasoconstrictor effects if given with ergot alkaloids or oxytocin. Co-admin with MAOIs may cause hypertensive crisis. Anaesthetics e.g. cyclopropane, halothane and other halogenated anaesthestics; antihypertensive agents.

UAD 22

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