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LORINASE Price

Active Substance: Loratadine, Pseudoephedrine sulfate.

16
UAD , based on 7541 reviews.
View Drug details

Overview

Welcome to Dwaey, specifically on LORINASE Tablets page.
This medicine contains an important and useful components, as it consists of Loratadine, Pseudoephedrine sulfate.
LORINASE is available in the market in concentration 5mg, 120mg/Tablet and in the form of Tablets.

SPIMACO (AL QASSIM PHARMACEUTICAL PLANT) is the producer of LORINASE and it is imported from SAUDI ARABIA, The most popular alternatives of LORINASE are listed downward .

Mode Of Action

Desloratadine is a long-acting, tricyclic, non-sedating, selective peripheral histamine H1-receptor antagonist which inhibits the release of pro-inflammatory mediators from human mast cells and basophils. Pseudoephedrine is both an ?-and ?-adrenergic receptor agonist. It causes vasoconstriction via direct stimulation of ?-adrenergic receptors of the respiratory mucosa. It also directly stimulates ?-adrenergic receptors causing bronchial relaxation, increased heart rate and contractility.

Indication

  • Allergic rhinitis
  • Itching
  • Sneezing
  • Watery eyes
  • Runny nose
  • Hives
  • Skin rash
  • Common cold
  • Nasal congestion

Precaution

Severe renal or hepatic failure; children <6 mth, elderly, epilepsy, pregnancy and lactation. Lactation: both drugs pass into breast milk, pseudoephedrine is concentrated in breast milk; use caution

Side Effects

  • >10% Desloratadine Fever (12%)
  • Irritability (12%)
  • Headache (12%)
  • Diarrhea (15-21%)
  • Cough (11%)
  • Upper respiratory tract infection (11-21%) 1-10% Desloratadine Pharyngitis (4.1%)
  • Dry mouth (3%)
  • Myalgia (2.1%)
  • Emotional lability (3%)
  • Erythema (3%)
  • Macopapular rash (3%)
  • Dizziness (4%)
  • Fatigue (2.1%)
  • Somnolence (2.1%)Urinary tract infection (4%)
  • Dyspepsia (3%)
  • Insomnia (5%)
  • Dysmenorrhea (2.1%) Frequency Not Defined Pseudoephedrine CNS (tremor
  • restlessness
  • etc)
  • Insomnia
  • Arrhythmia
  • Hypotension
  • Tachycardia
  • Fatigue
  • Rash
  • Urticaria
  • Anorexia
  • Xerostomia
  • Dysuria
  • Polyuria
  • Nausea
  • Vomiting
  • Ischemic colitis

Contra indication

Hypersensitivity.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Potential increase in plasma concentrations w/ drugs affecting hepatic microsomal enzymes (e.g. azithromycin, cimetidine, erythromycin, fluoxetine, ketoconazole). Increased risk of hypertension and arrhythmias if given with cardiac glycosides, quinidine or TCAs. Increased risk of vasoconstrictor effects if given with ergot alkaloids or oxytocin. Co-admin with MAOIs may cause hypertensive crisis. Anaesthetics e.g. cyclopropane, halothane and other halogenated anaesthestics; antihypertensive agents.

Alternatives Price List

  • LORINASEUAD 23
  • LORINASEUAD 16
  • LORINASEUAD 29

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