LETRO-DENK 2.5 Price

Overview

Welcome to Dwaey, specifically on LETRO-DENK 2.5 page.
This medicine contains an important and useful components, as it consists of
Letrozoleis available in the market in concentration

Name

Letrozole

Precaution

Severe renal impairment; severe hepatic impairment; osteoporosis. Caution when driving or operating machinery. Lactation: not known if excreted in breast milk (for post-menopausal women)

Indication

Breast cancer

Contra indication

Premenopausal women and children; hypersensitivity.

Side Effect

Hot flushes, arthralgia, nausea, vomiting, fatigue, dizziness, headache, dyspepsia, constipation, diarrhoea, anorexia, alopoecia, increased sweating, rash, peripheral oedema, osteoporosis, musculoskeletal pain, vaginal irritation. Potentially Fatal: Thromboembolic events.

Pregnancy Category ID

5

Mode of Action

Letrozole competitively binds to the heme group of aromatase, a cytochrome P450 enzyme which catalyzes conversion of androgen to oestrogen, leading to inhibition of the enzyme and a significant reduction in plasma oestrogen levels.

Interaction

Plasma levels reduced by tamoxifen.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration