DARAPRIM 25mg price in UAE

Overview

Welcome to Dwaey, specifically on DARAPRIM 25mg Tablets page.
This medicine contains an important and useful components, as it consists of Pyrimethamine.
DARAPRIM 25mg is available in the market in concentration 25mg/Tablet and in the form of Tablets.

THE WELLCOME FOUNDATION LIMITED is the producer of DARAPRIM 25mg and it is imported from UK, The most popular alternatives of DARAPRIM 25mg are listed downward .

Mode Of Action

Amitriptyline is a dibenzocycloheptadiene tricyclic antidepressant. It increases synaptic concentration of serotonin and/or norepinephrine in the CNS by blocking the neuronal reuptake of norepinephrine and serotonin.

Indication

Migraine headache
Depression
Neuropathic pain
Post-herpetic neuralgia
Nocturnal enuresis

Precaution

Bipolar illness, pregnancy, lactation elderly, CVS disease, renal or liver impairment, epilepsy, thyroid dysfunction, DM. Avoid abrupt withdrawal; urinary retention, prostatic hyperplasia; chronic constipation; angle-closure glaucoma; phaeochromocytoma. Monitor for signs of clinical worsening, suicidality or behavioural changes. May increase risks associated with electro-convulsive therapy. May affect ability to drive or operate machinery. Lactation: Distributed in breast milk; do not nurse (AAP states effect on nursing infants is unknown but may be of concern)

Side Effects

Postural hypotension
tachycardia
conduction disturbances. Dry mouth
wt gain
sour or metallic taste
stomatitis
constipation; blurring of vision
urinary retention
fatigue
dizziness
weakness
tremors
headache
confusion and delirium in elderly
sexual disturbances; peripheral neuropathy; urticaria
angioedema
sweating. Potentially Fatal: Cardiac arrhythmias.

Contra indication

Hypersensitivity, use of MAO inhibitors within the last 14 days; acute recovery phase post-MI. Concurrent usage with cisapride.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Increased risk of serotonin syndrome w/ SSRIs, TCAs, triptans, fentanyl, lithium, tramadol. May reduce plasma levels w/ barbiturates, rifampicin and other anticonvulsants. May increase plasma levels w/ methylphenidate, cimetidine, antipsychotics, Ca channel blockers. May precipitate cardiac arrhythmias w/ thyroid hormones. May reduce antihypertensive effects of debrisoquine, guanethidine and clonidine. May increase pressor effect of epinephrine and norepinephrine. May increase the risk of ventricular arrhythmias w/ antiarrhythmics (e.g. amiodarone or quinidine), antihistamines astemizole, terfenadine, some antipsychotics (pimozide, sertindole, and thioridazine), sotalol, cisapride and halofantrine. Potentially Fatal: Increased risk of serotonin syndrome w/ MAOIs, linezolid and methylene blue.