IRBIGEN-H 300/12.5 price in UAE

Overview

Welcome to Dwaey, specifically on IRBIGEN-H 300/12.5 Tablets/Film-coated page.
This medicine contains an important and useful components, as it consists of Irbesartan, Hydrochlorothiazide.
IRBIGEN-H 300/12.5 is available in the market in concentration 300mg, 12.5mg/Tablet and in the form of Tablets/Film-coated.

NEXGEN PHARMA FZ LLC is the producer of IRBIGEN-H 300/12.5 and it is imported from UAE, The most popular alternatives of IRBIGEN-H 300/12.5 are listed downward .

Mode Of Action

Hydrochlorothiazide inhibits the reabsorption of Na and chloride in the distal tubules causing increased excretion of Na and water K and hydrogen ions. Irbesartan is an angiotensin II receptor antagonist. It blocks the vasoconstricting and aldosterone-secreting effects of angiotensin II by binding to AT1 receptors.

Indication

Diabetic nephropathy
Hypertension

Precaution

Child <6 yr. Unilateral or bilateral renal artery stenosis; vol or Na depletion; aortic or mitral valve stenosis, hypertrophic cardiomyopathy. Lactation: discontinue drug or do not nurse

Side Effects

>10% Irbesartan Hyperkalemia (19%) 1-10% Chest pain (2%)
Tachycardia (1%)
Abnormal urination (2%)
Musculoskeletal pain (6%)
Flu-like syndrome (3%)
Edema (3%)
Tachycardia (1%)
Chest pain (2%)
Creatinine increased (1%)
Increased BUN (2%) Irbesartan Dizziness (10%)
URI (9%)
Orthostatic hypotension (5%)
Fatigue (4%)
Diarrhea (3%)
Dyspepsia (2%) Frequency Not Defined Hydrochlorothiazide Anorexia
Epigastric distress
Hypotension
Orthostatic hypotension
Photosensitivity
Anaphylaxis
Anemia
Confusion
Erythema multiforme
Stevens-Johnson syndrome
Exfoliative dermatitis including toxic epidermal necrolysis
Dizziness
Hypokalemia and/or hypomagnesemia
Hyperuricemia
Headache

Contra indication

Hypersensitivity; pregnancy and lactation.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Pregnancy Category: C (1st trimester); D (2nd & 3rd trimesters)

Interaction

Other antihypertensives, lithium, K-sparing diuretics, K supplements, salt substitutes containing K. CNS depressants, antidiabetics, cholestyramine & colestipol resins, corticosteroids, ACTH, digitalis glycosides, antiarrhythmics, NSAIDs, tubocurarine, antigout medications, Ca salts. Alcohol; ?-blockers, diazoxide, atropine, beperiden, amantadine, cyclophosphamide, methotrexate.