INVANZ 1g Price

Overview

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This medicine contains an important and useful components, as it consists of
Ertapenem (as sodium)is available in the market in concentration

Name

Ertapenem

Precaution

Hypersensitivity to penicillins, cephalosporins or other beta-lactams (possibility of cross-sensitivity). Renal impairment; CNS disorders e.g. epilepsy. Pregnancy. Lactation: Drug distributed in breast milk; use with caution

Indication

Intra-abdominal infections, Community-acquired pneumonia, Skin and skin structure infections, Urinary tract infections, Pyelonephritis, Surgical infections, Diabetic foot infections, Septic abortion

Contra indication

Hypersensitivity; lactation.

Side Effect

>10% Diarrhea (2-12%) 1-10% Elevated liver function tests (LFTs) (7-9%),Nausea (6-9%),Headache (6-7%),Infused vein complications (5-7%),Increased platelet count (4-7%),Increased alkaline phosphatase (4-7%),Altered mental status (3-5%),Fever (2-5%),Abdominal pain (4%),Vomiting (4%),Constipation (3-4%),Insomnia (3%),Swelling or edema (3%),Drug rash with eosinophilia and systemic symptoms (DRESS syndrome) (2-3%),Rash (2-3%),Vaginitis (1-3%),Dizziness (2%),Phlebitis or thrombophlebitis (1.5-2%),Pruritus (1-2%),Tachycardia (1-2%),Acid regurgitation (1-2%),Eosinophilia (1-2%),Hypotension (1-2%),Erythema (1-2%),Hypertension (0.7-2%),Chest pain (1%),Dyspepsia (1%),Fatigue (1%),Anxiety (0.8-1%),Oral candidiasis (0.1-1%) Potentially Fatal: Pseudomembranous colitis, Stevens-Johnson syndrome.

Pregnancy Category ID

2

Mode of Action

Ertapenem acts similarly to penicillins by bacterial cell wall inhibition. It is active against many gram-negative and aerobic and anaerobic organisms. It is stable to hydrolysis by beta-lactamases.

Interaction

May decrease plasma levels of valproic acid thus, increasing the risk of seizures. Increased plasma concentrations w/ probenecid.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration