Active Substance: Etonogestrel.
Overview
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This medicine contains an important and useful components, as it consists of
Etonogestrelis available in the market in concentration
Etonogestrel
Heart disease, sex-steroid dependent cancer, history of ectopic pregnancy, malabsorption syndromes, functional ovarian cysts, recurrent cholestatic jaundice, history of jaundice in pregnancy; history of pruritus during pregnancy or of deterioration of otosclerosis; disturbances of lipid metabolism; history of CV or renal impairment, DM, asthma, epilepsy, migraine, depression; lactation. May develop bleeding irregularities. Lactation: Small amounts excreted in breast milk; may nurse after the 4th postpartum week
Contraception
Pregnancy, undiagnosed vag bleeding, severe arterial disease; liver adenoma; active liver disease; current or history of thromboembolic disorders; porphyria; after evacuation of hydatidiform mole; history of breast cancer.
>10% Oligomenorrhea (34%),Headache (25%),Vaginitis (24.5%),Amenorrhea (22%),Menorrhagia (18%),Weight gain (14%),Acne (13.5%),Breast pain (13%),Upper resp tract infection (13%),Pharyngitis (11%),Leucorrhea (10.5%) 1-10% Back pain (7%),Depression (6%),Dizziness (7%),Dysmenorrhea (7%),Emotional lability (7%),Flu-like symptoms (8%),Insertion-site pain (9%),Nausea (6%),Nervousness (6%),Pain (6%)
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Etonogestrel is the active metabolite of desogestrel. It prevents pregnancy by suppressing ovulation, increasing viscosity of cervical mucous and inhibiting endometrial proliferation.
Reduced efficacy with hepatic enzyme-inducing drugs; aminoglutethimide. May inhibit ciclosporin metabolism. Changes in efficacy and safety of treatment when used in combination with protease inhibitors.
Information not available