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HIZENTRA 200 mg/ml Price

Active Substance: Human immunoglobulin (Human plasma protein with purity of ³ 98% IgG).

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Overview

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This medicine contains an important and useful components, as it consists of
Human immunoglobulin (Human plasma protein with purity of ³ 98% IgG)is available in the market in concentration

Name

Human normal Immunoglobulin

Precaution

For IV use only. Pregnancy, lactation.

Indication

Immunocompromised patients or patients with primary antibodies deficiency, Prophylaxis of infections after bone marrow transplantation, Allogenic bone marrow transplantation.

Contra indication

Hypersensitivity to human Ig, circulating Abs to IgA.

Side Effect

Occasionally, chills, headache, fever, allergic reactions, nausea, arthralgia & mild back pain. In particular cases & esp after high IV doses, reversible aseptic meningitis & impaired renal function (dose-dependent) may occur. Rarely, fall in BP. In isolated cases, anaphylactic shock.

Pregnancy Category ID

3

Mode of Action

Human normal immunoglobulin is derived from donations of pooled human plasma. It contains antibodies, mainly immunoglobulin G (IgG), to various bacteria and viruses present in the general population such as hepatitis A, measles, mumps, rubella and varicella. It has a distribution of IgG subclasses that is very close to that of the normal human plasma. It is therefore, used to provide passive immunisation against such diseases.

Interaction

May interfere with the immune response to live measles vaccine, live mumps vaccine, live rubella vaccine and live varicella vaccine, therefore these vaccines should be given at least 3 wk before or 3 mth after the admin of the immunoglobulins.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration

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