HISTALOC 25mg price in UAE

Overview

Welcome to Dwaey, specifically on HISTALOC 25mg Tablets/Film-coated page.
This medicine contains an important and useful components, as it consists of Promethazine HCl.
HISTALOC 25mg is available in the market in concentration 25mg/Tablet and in the form of Tablets/Film-coated.

JULPHAR (GULF PHARMACEUTICAL INDUSTRIES) is the producer of HISTALOC 25mg and it is imported from UAE, The most popular alternatives of HISTALOC 25mg are listed downward .

Mode Of Action

Promethazine, a phenothiazine derivative, blocks postsynaptic dopaminergic receptors in the brain and has a strong alpha-adrenergic blocking effect. It competitively binds to H1-receptors.

Indication

Allergic conditions
Nausea and vomiting
Motion sickness
Insomnia

Precaution

Patient w/ asthma, bronchitis or bronchiectasis; severe coronary artery disease, narrow-angle glaucoma, epilepsy, bladder neck or pyloro-duodenal obstruction, Reye's syndrome, bone marrow depression, Hepatic and renal impairment. Pregnancy and lactation. Patient Counselling This drug may cause marked drowsiness, if affected, do not drive or operate machinery. Avoid prolonged exposure to sunlight. Monitoring Parameters Monitor mental status; signs and symptoms of tissue injury (IV inj). Lactation: Not known whether drug crosses into breast milk; discontinue drug, or do not nurse

Side Effects

Neuroleptic Malignant Syndrome (NMS); CV effects (e.g. bradycardia
tachycardia
transient HTN
hypotension; jaundice
blood dyscrasias
extrapyramidal effects; IV inj: Severe tissue injury (e.g. gangrene)
pain and burning
paralysis
thrombophlebitis
severe spasm of distal vessels
necrosis. Sedation
Confusion
Disorientation
Blurred vision
Hallucinations
Dystonias
Catatonic states
Euphoria
Excitation
Impotence
Urinary retention Potentially Fatal: Resp depression and apnoea esp in childn.

Contra indication

Patients in coma or suffering from CNS depression of any cause. Childn <2 yr. SC and intra-arterial admin. Concurrent use w/ or w/in 14 days of MAOI use.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Masks ototoxicity of aminoglycoside antibiotics. May enhance the sedative effects of CNS depressants like alcohol, hypnotics, barbiturates and opioids. Potentially Fatal: Ventricular arrhythmias when used with drugs that prolong QT interval. Increased risk of extrapyramydal effects w/ MAOIs.