GLUCOSTRA XR 500mg Price

Overview

Welcome to Dwaey, specifically on GLUCOSTRA XR 500mg Tablets/Prolonged Release page.
This medicine contains an important and useful components, as it consists of Metformin Hydrochloride.
GLUCOSTRA XR 500mg is available in the market in concentration 500mg/Tablet and in the form of Tablets/Prolonged Release.

LIFEPHARMA FZE is the producer of GLUCOSTRA XR 500mg and it is imported from UAE, The most popular alternatives of GLUCOSTRA XR 500mg are listed downward .

Mode Of Action

Metformin is a biguanide w/ antihyperglycaemic effects, lowering both basal and postprandial plasma glucose. It decreases hepatic glucose production by inhibiting gluconeogenesis and glycogenolysis; delays intestinal absorption of glucose; and enhances insulin sensitivity by increasing peripheral glucose uptake and utilisation.

Indication

• Type 2 DM
• Polycystic ovarian syndrome

Precaution

Caution when used in patients with CHF especially in those with unstable or acute heart failure. Risk of lactic acid accumulation increases with the degree of renal impairment. May need to discontinue treatment in patients with stress-related states e.g. fever, trauma, infection or surgery. Metformin should be temporarily discontinued for 48 hr in patients undergoing radiologic studies involving intravascular admin of iodinated contrast materials. Elderly. Monitor renal function regularly. Because of possibility of hypoglycemia in combination therapy with a sulphonylurea or insulin, diabetic control should be monitored by blood sugar readings. Lactation: Enters breast milk; not recommended

Side Effects

• Anorexia
• nausea
• vomiting
• diarrhoea
• wt loss
• flatulence
• occasional metallic taste; weakness; hypoglycaemia; rash
• malabsorption of vit B12. Chest discomfort
• flushing
• palpitation
• chills
• headache
• lightheadedness
• indigestion
• abdominal discomfort. Potentially Fatal: Lactic acidosis in presence of renal failure and alcoholism. Patients may experience a metallic taste and there may be weight loss
• which in some diabetics could be an advantage.

Contra indication

Acute or chronic metabolic acidosis with or without coma (including diabetic ketoacidosis). Renal failure, severe renal or hepatic impairment, acute conditions which may affect renal function e.g. dehydration, severe infection or shock. Cardiac failure, CHF, IDDM, severe impairment of thyroid function; acute or chronic alcoholism. Acute or chronic diseases which may cause tissue hypoxia e.g. cardiac or respiratory failure, recent MI or shock. Pregnancy, lactation.

Pregnancy and lactation

Pregnancy category: B

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.