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GLUCORMINXR 500 mg Price

Active Substance: Metformin Hydrochloride.

10
UAD , based on 7541 reviews.
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Overview

Welcome to Dwaey, specifically on GLUCORMINXR 500 mg Prolonged release tablet page.
This medicine contains an important and useful components, as it consists of Metformin Hydrochloride.
GLUCORMINXR 500 mg is available in the market in concentration 500 mg/Tablet and in the form of Prolonged release tablet.

PHARMAX PHARMACEUTICALS FZ LLC is the producer of GLUCORMINXR 500 mg and it is imported from UAE, The most popular alternatives of GLUCORMINXR 500 mg are listed downward .

Mode Of Action

Metformin is a biguanide w/ antihyperglycaemic effects, lowering both basal and postprandial plasma glucose. It decreases hepatic glucose production by inhibiting gluconeogenesis and glycogenolysis; delays intestinal absorption of glucose; and enhances insulin sensitivity by increasing peripheral glucose uptake and utilisation.

Indication

  • Type 2 DM
  • Polycystic ovarian syndrome

Precaution

Caution when used in patients with CHF especially in those with unstable or acute heart failure. Risk of lactic acid accumulation increases with the degree of renal impairment. May need to discontinue treatment in patients with stress-related states e.g. fever, trauma, infection or surgery. Metformin should be temporarily discontinued for 48 hr in patients undergoing radiologic studies involving intravascular admin of iodinated contrast materials. Elderly. Monitor renal function regularly. Because of possibility of hypoglycemia in combination therapy with a sulphonylurea or insulin, diabetic control should be monitored by blood sugar readings. Lactation: Enters breast milk; not recommended

Side Effects

  • Anorexia
  • nausea
  • vomiting
  • diarrhoea
  • wt loss
  • flatulence
  • occasional metallic taste; weakness; hypoglycaemia; rash
  • malabsorption of vit B12. Chest discomfort
  • flushing
  • palpitation
  • chills
  • headache
  • lightheadedness
  • indigestion
  • abdominal discomfort. Potentially Fatal: Lactic acidosis in presence of renal failure and alcoholism. Patients may experience a metallic taste and there may be weight loss
  • which in some diabetics could be an advantage.

Contra indication

Acute or chronic metabolic acidosis with or without coma (including diabetic ketoacidosis). Renal failure, severe renal or hepatic impairment, acute conditions which may affect renal function e.g. dehydration, severe infection or shock. Cardiac failure, CHF, IDDM, severe impairment of thyroid function; acute or chronic alcoholism. Acute or chronic diseases which may cause tissue hypoxia e.g. cardiac or respiratory failure, recent MI or shock. Pregnancy, lactation.

Pregnancy and lactation

Pregnancy category: B

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Interaction

Additive effect w/ sulfonylureas. Thiazide diuretics, corticosteroids, phenothiazines, OC, sympathomimetics, niacin, Ca channel blockers and isoniazid may exacerbate loss of glycaemic control. ACE inhibitors may reduce fasting blood glucose concentrations. May increase serum level w/ cimetidine. Potentially Fatal: Concurrent use w/ iodinated contrast agents may increase the risk of metformin-induced lactic acidosis.

Alternatives Price List

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  • METSWIFT XR 500mg UAD 9
  • METSWIFT XR 1000mg UAD 14
  • GLUCOSTRA XR 750mg UAD 22
  • GLUCOSTRA XR 500mg UAD 18

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