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GLUCOBAY 50 Price

Active Substance: Acarbose.

22
UAD , based on 7541 reviews.
View Drug details

Overview

Welcome to Dwaey, specifically on GLUCOBAY 50 Tablets page.
This medicine contains an important and useful components, as it consists of Acarbose.
GLUCOBAY 50 is available in the market in concentration 50mg/Tablet and in the form of Tablets.

BAYER HEALTHCARE AG is the producer of GLUCOBAY 50 and it is imported from GERMANY, The most popular alternatives of GLUCOBAY 50 are listed downward .

Mode Of Action

Acarbose competitively and reversibly inhibits pancreatic alpha-amylase and intestinal brush border alpha-glucosidases, resulting in retardation of glucose absorption from hydrolysed complex carbohydrates and reduction of blood-glucose concentrations.

Indication

  • Type 2 DM

Precaution

Monitor LFT every 3 mth for 1st yr and periodically thereafter especially for doses >50 mg tid. Reduce dose or withdraw therapy if transaminases elevations persist. If hypoglycaemia occurs, give glucose orally as a 1st aid measure. Adhere strictly to the prescribed diabetic diet to avoid intensification of GI symptoms. Lactation: not known if crosses into breast milk, avoid using in nursing women.

Side Effects

  • >10% abdominal pain (19%)
  • diarrhea (31%)
  • elevated serum transaminases
  • flatulence (74%) Potentially Fatal: Hepatotoxicity.

Contra indication

Patients <18 yr; diabetic ketoacidosis or cirrhosis; malabsorption; inflammatory bowel disease; with or pre-disposed to intestinal obstruction; intestinal diseases that affect digestion or absorption; conditions that worsen as a result of increased gas formation e.g. hernias; colonic ulcers; hepatic impairment; CrClr< 25 ml/min/1.73m2. Pregnancy, lactation.

Pregnancy and lactation

Pregnancy category: B

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Interaction

May enhance effects of other antidiabetics including insulin. Diminished effects w/ GI adsorbents (e.g. charcoal) and digestive enzyme preparations containing carbohydrate splitting enzymes (e.g. amylase, pancreatin). Neomycin and colestyramine may enhance effects of acarbose. May inhibit absorption of digoxin.

Alternatives Price List

  • GLUCOBAY 50UAD 22
  • GLUCOBAY 100UAD 28

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