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Overview

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Name

Sodium Carboxymethyl-cellulose 10 mg ml

Precaution

Before using **Sodium Carboxymethyl-cellulose (CMC)** 10 mg/mL, it is important to consult with a healthcare provider, particularly if you have any pre-existing conditions or are taking other medications. The following precautions should be considered: - **Allergic Reactions**: Although rare, some individuals may experience an **allergic reaction** to carboxymethyl cellulose. Signs of an allergic reaction may include **rash**, **swelling**, **itching**, or **difficulty breathing**. If any of these symptoms occur, it is crucial to seek immediate medical attention. - **Eye Irritation**: For products used in **ocular preparations**, patients should be cautious if they have a history of eye conditions such as **dry eye syndrome** or **conjunctivitis**. Sodium carboxymethyl cellulose is often used as an eye lubricant, but prolonged use or incorrect application can lead to **irritation** or **discomfort**. - **Pregnancy and Breastfeeding**: Generally, **Sodium Carboxymethyl-cellulose** is considered safe during pregnancy and breastfeeding. However, it is always important to discuss with a healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding before using any product containing this substance. - **Renal Function**: Although Sodium Carboxymethyl-cellulose is generally well-tolerated, it is important to consult with a healthcare provider before using it in individuals with **renal impairment**, especially if being used in larger quantities or for prolonged periods.

Indication

**Sodium Carboxymethyl-cellulose (CMC)** is a versatile compound that has a wide range of therapeutic uses, particularly in eye care and as a stabilizer in certain medical formulations. Its primary indications include: - **Dry Eye Disease**: Sodium Carboxymethyl-cellulose is widely used as a **lubricating eye drop** to provide relief from symptoms of **dry eye syndrome**. It helps to rehydrate the eyes by acting as a tear substitute, alleviating dryness, irritation, and discomfort caused by insufficient tear production. - **Eye Irritation**: It is commonly used to soothe **mild eye irritation** resulting from environmental factors like **wind**, **smoke**, or **long screen use**. - **Ocular Surgery**: Sodium Carboxymethyl-cellulose is used during certain types of **ocular surgeries** (e.g., cataract surgery) to help protect the eye and maintain the integrity of the corneal tissue. - **Wound Healing**: It is sometimes used in wound care, as it provides a moist environment conducive to **healing**. - **Topical Applications**: Sodium CMC is also included in certain **topical ointments** and **creams** to enhance moisture retention and act as a **vehicle** for other medicinal agents.

Contra indication

**Sodium Carboxymethyl-cellulose** should not be used in the following situations: - **Hypersensitivity**: Individuals who are allergic or sensitive to **carboxymethyl cellulose** or any components of the formulation should avoid using it. This can cause an allergic reaction, including skin rashes, swelling, and difficulty breathing. - **Eye Infections**: Sodium Carboxymethyl-cellulose should not be used for treating **eye infections**, as it is not an antimicrobial agent. If there is an infection present in the eye, appropriate antibiotic or antiviral treatments should be used instead. - **Pre-existing Eye Conditions**: In patients with severe eye conditions such as **glaucoma**, or those with a history of significant eye surgeries, it is advised to use this product under medical supervision.

Side Effect

Sodium Carboxymethyl-cellulose is generally well-tolerated, but some side effects may occur: - **Eye Irritation**: When used as eye drops, it can cause **temporary stinging**, **burning**, or **blurred vision** immediately after application. These side effects typically subside shortly after use. - **Allergic Reactions**: Although rare, some individuals may experience signs of an **allergic reaction**, including redness, swelling, itching, or rashes around the eyes or on the skin. - **Increased Eye Discomfort**: If not properly used, the gel-like consistency of Sodium CMC can sometimes lead to **increased discomfort** or **foreign body sensation** in the eyes. - **Blurred Vision**: As it temporarily thickens the tear film, Sodium CMC may cause **blurred vision** for a short period after application. This is generally transient and resolves after blinking. - **Dryness or Discomfort in Eyes**: Prolonged or excessive use of Sodium CMC can occasionally lead to **increased dryness** or **discomfort** in the eyes, especially if the product is not applied properly or used in excess.

Pregnancy Category ID

0

Mode of Action

**Sodium Carboxymethyl-cellulose (CMC)** works primarily as a **lubricant** and **viscosity enhancer**. When applied to the eye, CMC mimics the natural tear film by forming a **viscous layer** that helps to: - **Moisten the Surface of the Eye**: Sodium CMC acts as a **tear substitute**, providing moisture to the eye's surface, which is essential for those suffering from **dry eye disease** or other conditions that reduce tear production. - **Protect the Cornea**: It helps to reduce **friction** between the eyelid and cornea during blinking, thereby preventing **irritation** and damage to the corneal surface. - **Relieve Discomfort**: The gel-like consistency of sodium CMC also provides a **soothing effect**, reducing the burning, stinging, or dryness that patients with eye discomfort experience.

Interaction

Sodium Carboxymethyl-cellulose itself does not have many known drug interactions, but the following should be kept in mind: - **Other Eye Medications**: When using Sodium CMC eye drops with other eye medications, it’s important to **space out the application** of different medications by at least **10–15 minutes** to avoid interfering with the effectiveness of other treatments. - **Topical Medications**: For topical use, the **absorption** of other medications through the skin may be slightly altered by the use of Sodium CMC. However, it is not typically known to significantly interact with topical agents. - **Contact Lenses**: If using Sodium CMC for **dry eye relief**, it should be noted whether the product is specifically **safe for use with contact lenses**. Some formulations may contain preservatives or agents that could damage the lenses or cause discomfort. Always consult the product's guidelines before use with contact lenses.

Pregnancy Category Note

Information not available

Adult Dose

The dosing of **Sodium Carboxymethyl-cellulose** depends on the form and the condition being treated. For **ocular use**, typical dosing guidelines are as follows: - **Eye Drops**: - **1 to 2 drops** in the affected eye(s), **2 to 3 times daily** or as needed. - For **severe dry eye disease**, higher-frequency use or gel formulations may be recommended. - **Topical Ointment**: - Applied to the affected area **1 to 2 times daily**, as per the healthcare provider’s recommendations.

Child Dose

**Sodium Carboxymethyl-cellulose** can be used in children, especially for **dry eye** conditions, under the guidance of a healthcare provider. Typical pediatric dosing is: - **Children** (ages 2 years and older): - **1 drop** in the affected eye(s), **2 to 3 times daily**, or as directed by a pediatrician. - For more severe cases of dry eyes or other eye conditions, the dose may vary according to the doctor’s instructions. For children under **2 years old**, it is recommended to seek medical advice before using this medication to ensure safety and appropriate usage.

Renal Dose

Sodium Carboxymethyl-cellulose does not require dose adjustments for patients with **renal impairment** since it is not systemically absorbed to any significant degree. However, if used in larger quantities or for prolonged periods, the effects on renal function should be monitored, particularly in individuals with severe renal disease.

Administration

Information not available