GAMCET 0.4mg Price

Overview

Welcome to Dwaey, specifically on GAMCET 0.4mg Tablet/ Prolonged Release Film Coated page.
This medicine contains an important and useful components, as it consists of Tamsulosin HCl.
GAMCET 0.4mg is available in the market in concentration 0.4 mg/Tablet and in the form of Tablet/ Prolonged Release Film Coated .

DAR AL DAWA DEVELOPMENT & INVESTMENT CO. LTD. is the producer of GAMCET 0.4mg and it is imported from Jordan, The most popular alternatives of GAMCET 0.4mg are listed downward .

Mode Of Action

Tamsulosin is a selective alpha1 adrenoreceptor-blocking agent. Smooth muscle tone is mediated by the sympathetic nervous stimulation of alpha1 adrenoreceptors, which are abundant in the prostate, prostatic capsule, prostatic urethra, and bladder neck. Blockade of these adrenoceptors can cause smooth muscles in the bladder neck and prostate to relax, resulting in an improvement in urine flow rate and reduction in symptoms in BPH.

Indication

• Benign prostatic hyperplasia

Precaution

Hypersensitivity to Tamsulosin Hydrochloride. A history of orthostatic hypotension; severe hepatic insufficiency. As with other alpha1 blockers, a reduction in blood pressure can occur in individual cases during treatment with Tamsulosin, as a result of which, rarely, syncope can occur. At the first signs of orthostatic hypotension (dizziness, weakness) the patient should sit or lie down until the symptoms have disappeared. And they should be cautioned to avoid situations where injury could result (like driving, operating machinery or performing hazardous tasks). Before therapy with Tamsulosin is initiated the patient should be examined in order to exclude the presence of other conditions which can cause the same symptoms as Benign Prostatic Hyperplasia. Digital rectal examination and when necessary determination of Prostate Specific Antigen (PSA) should be performed before treatment and at regular intervals afterwards. The treatment of severely renal impaired patients (creatinine clearance is less than10ml/min) should be approached with caution as these patients have not been studied. Caution should be exercised in porphyria or allergic reaction to this or any other medicine.

Side Effects

• >10% Headache (19-21%)
• Orthostatic hypotension (6-19%)
• Rhinitis (13-18%)
• Abnormal ejaculation (8-18%)
• Dizziness (15-17%)
• Arthralgia (11%)
• Infection (9-11%) 1-10% Asthenia (8%)
• Back pain (7-8%)
• Skin rash (7%)
• Pharyngitis (5-6%)
• Diarrhea (4-6%)
• Myalgia (5%)
• Chest pain (4%)
• Cough (3-4%)
• Somnolence (3-4%)
• Nausea (2-4%)
• Sinusitis (2-4%)
• Abdominal discomfort (2-3%)
• Bitter taste (2-3%)
• Decreased libido (1-2%)
• Insomnia (1-2%)

Contra indication

Hypersensitivity to sulfonamide, severe hepatic impairment, lactation. History of orthostatic hypotension.

Pregnancy and lactation

Pregnancy category: B

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.