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FUROKERN 40mg Price

Active Substance: Furosemide .

12
UAD , based on 7541 reviews.
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Overview

Welcome to Dwaey, specifically on FUROKERN 40mg Tablet page.
This medicine contains an important and useful components, as it consists of Furosemide .
FUROKERN 40mg is available in the market in concentration 40 mg/tablet and in the form of Tablet .

KERN PHARMA S.L., is the producer of FUROKERN 40mg and it is imported from SPAIN, The most popular alternatives of FUROKERN 40mg are listed downward .

Mode Of Action

Furosemide inhibits reabsorption of Na and chloride mainly in the medullary portion of the ascending Loop of Henle. Excretion of potassium and ammonia is also increased while uric acid excretion is reduced. It increases plasma-renin levels and secondary hyperaldosteronism may result. Furosemide reduces BP in hypertensives as well as in normotensives. It also reduces pulmonary oedema before diuresis has set in.

Indication

  • Hypertension
  • Congestive heart failure
  • Nephrotic syndrome
  • Hypercalcemia
  • Edema
  • Cirrhosis
  • Renal impairment
  • Cerebral/pulmonary edema
  • Pulmonary oedema
  • Acute renal failure
  • Chronic renal failure

Precaution

Prostatic hyperplasia. Hepatic or renal impairment, gout, DM, impaired micturition. Infusion rate should not exceed 4 mg/min to reduce the risk of ototoxicity. Monitor fluid and electrolyte balance and renal function. May lower serum levels of calcium and magnesium, thus serum levels should be monitored. Pregnancy and lactation. Lactation: Drug excreted into breast milk; use with caution; may inhibit lactation

Side Effects

  • >10% Hyperuricemia (40%)
  • Hypokalemia (14-60%) Frequency Not Defined Hyponatraemia
  • hypochloraemic alkalosis
  • headache
  • drowsiness
  • muscle cramps
  • hypotension
  • dry mouth
  • thirst
  • weakness
  • lethargy
  • restlessness
  • oliguria
  • GI disturbances
  • hypovolaemia
  • dehydration
  • hyperuricaemia
  • acute generalised exanthematous pustulosis
  • drug rash w/ eosinophilia and systemic symptoms
  • reversible or irreversible hearing impairment
  • deafness
  • tinnitus
  • severe anaphylactic or anaphylactoid reactions (e.g. w/ shock)
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis; increased liver enzyme
  • cholesterol and triglyceride serum levels. Potentially Fatal: Serious cardiac arrhythmias.

Contra indication

Severe sodium and water depletion, hypersensitivity to sulphonamides and furosemide, hypokalaemia, hyponatraemia, precomatose states associated with liver cirrhosis, anuria or renal failure. Addison's disease.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Analgesics reduce natriuretic action of furosemide. Antagonises hypoglycaemic agents and drugs used for gout. Hyperglycaemia with antihypertensive agent diazoxide. Antagonises muscle relaxants. Increased risk of ototoxicity when used with aminoglycosides especially in renal impairment. May enhance nephrotoxicity of cephalosporins. Effects of antihypertensives enhanced. Action antagonised by corticosteroids. Phenytoin and indometacin may reduce effects of furosemide. Potentially Fatal: May provoke severe hypotensive response with ACE inhibitors. NSAIDs inhibit diuretic and antihypertensive effects. Increased incidence of premature beats with cardiac glycosides.

Alternatives Price List

  • FUROKERN 40mgUAD 12

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