FRAGMIN 5000 IU (anti-Xa) _ Price

Overview

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This medicine contains an important and useful components, as it consists of
Dalteparin sodiumis available in the market in concentration

Name

Dalteparin Sodium

Precaution

Preexisting thrombocytopenia, recent childbirth, DM, subacute bacterial endocarditis, pericarditis, recent lumbar puncture, vasculitis. Monitor coagulation time. Hepatic or renal dysfunction; high doses; osteoporosis; familial antithrombin III deficiency; elderly; children; platelet count and stool occult blood test recommended during treatment; GI ulceration. Pregnancy and lactation. Lactation: Enters breast milk; use with caution

Indication

Unstable angina, Pulmonary embolism, Deep-vein thrombosis, Prophylaxis of clotting in extracorporeal circulation in haemodialysis or haemofiltration, Prophylaxis of venous thromboembolism during surgery

Contra indication

Hypersensitivity. Active major bleeding, severe coagulation disorders; lumbar puncture; sympathetic block; brain, spinal cord, eye or ear surgery; severe hypertension.

Side Effect

1-10% Injection site hematoma (7-35%),Thrombocytopenia (10.9-13.6%, patients with cancer ),Injection site pain (4.5-12%),Major hemorrhage (up to 4.6%),Increased liver function test (up to 4.3%),Wound hematoma,Hematuria Frequency Not Defined Epidural hematoma,Spinal hematoma,Hemorrhagic cerebral infarction,Intracranial hemorrhage,Intrauterine subdural hemorrhage,Thrombocytopenia (<1%, non-cancer indications),Anaphylactoid reaction (rare) Potentially Fatal: Severe haemorrhage.

Pregnancy Category ID

2

Mode of Action

Dalteparin sodium is a low molecular weight heparin analogue which inhibits factor Xa more than factor IIa (thrombin).

Interaction

Increased risk of haemorrhage w/ other anticoagulant/antiplatelet agents (e.g. aspirin/dipyridamole, glycoprotein IIb/IIIa receptor antagonists, vit K antagonists, NSAIDs, cytostatics, dextran, thrombolytics, sulfinpyrazone, probenecid, etacrynic acid). Reduced anticoagulant effect w/ antihistamines, cardiac glycosides, tetracycline and ascorbic acid.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration