FLUOROURACIL 500mg/20ml Price

Overview

Welcome to Dwaey, specifically on FLUOROURACIL 500mg/20ml Injection page.
This medicine contains an important and useful components, as it consists of Fluorouracil.
FLUOROURACIL 500mg/20ml is available in the market in concentration 25mg/ml and in the form of Injection.

DAVID BULL LABORATORIES is the producer of FLUOROURACIL 500mg/20ml and it is imported from AUSTRALIA, The most popular alternatives of FLUOROURACIL 500mg/20ml are listed downward .

Mode Of Action

Fluorouracil interferes with DNA synthesis by blocking the conversion of deoxyuridylic acid to thymidylic acid. It also interferes with RNA synthesis. This results in an unbalanced growth of the cells. Fluorouracil exerts greater effect on rapidly growing cells as they take up the drug at a faster rate.

Indication

• Palliation of malignant neoplasms
• Superficial basal cell carcinoma
• Oesophageal carcinoma
• Cancers of Colon
• Breast
• Ovary
• Liver
• Pancreas
• Rectum
• Stomach

Precaution

Regular monitoring of blood counts. History of heart disease, hepatic or renal insufficiency, weak or malnourished patients, patients who with history of high-dose pelvic radiation or use of alkylating agents. Patients with widespread metastases to the bone marrow. Lactation: excretion in milk unknown; do not nurse.

Side Effects

• 1-10% Loss of appetite
• Headache
• Nausea
• Vomiting
• Diarrhea
• Mucositis
• Myelosuppression
• Alopecia
• Photosensitivity
• Hand-foot syndrome
• Maculopapular eruption (pruritic) Frequency Not Defined Angina
• Coronary arteriosclerosis
• Thrombophlebitis
• Darkening of veins
• Gastrointestinal ulcer
• Increased alkaline phosphatase
• Increased LFTs
• Hyperbilirubinemia
• Hypercholesterolemia (increased LDH)
• Anaphylaxis
• Nystagmus
• Ophthalmic findings Potentially Fatal: Central neurotoxicity
• myocardial ischaemia.

Contra indication

Topical application on mucous membranes, exposure to sunlight, hypersensitivity. Depressed bone marrow function, poor nutritional status, potentially serious infections. Pregnancy and lactation.

Pregnancy and lactation

Pregnancy category: D

There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.