Active Substance: Fexofenadine HCl.
Overview
Welcome to Dwaey, specifically on FEXOGEN 180 page.
This medicine contains an important and useful components, as it consists of
Fexofenadine HClis available in the market in concentration
Fexofenadine Hydrochloride
Renal impairment. Pregnancy, lactation; children <6 yr. Lactation: Excretion in milk unknown; use with caution (AAP states “compatible with nursing”)
Allergic rhinitis, Hay fever, Urticaria, Allergy
Hypersensitivity.
>10% Vomiting (6-12%) 1-10% Headache (5-10%),Cough (4%),Diarrhea (3-4%),URTI (3%),Back pain (2-3%),Pyrexia (2%),Dysmenorrhea (2%),Dizziness (2%),Stomach discomfort (2%),Pain in extremity (2%),Somnolence (1-3%),Rhinorrhea (1-2%)
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Fexofenadine, an active metabolite of terfenadine, is a competitive peripheral histamine H1-receptor antagonist on effector cells in the GI tract, blood vessels and respiratory tract.
Co-admin with ketoconazole or erythromycin may increase plasma levels of fexofenadine. May increase adverse effects of other anticholinergics and CNS depressants. May increase arrhythmogenic effect of antipsychotic agents (phenothiazines); avoid concurrent usage. May reduce the efficacy of betahistine. Pramlintide may increase the anticholinergic effect of fexofenadine. Bioavailability may be increased by verapamil. Efficacy may be reduced by rifampin.
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