FERRASIL Price

Overview

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This medicine contains an important and useful components, as it consists of
Iron Sucroseis available in the market in concentration

Name

Elemental Iron (Iron sucrose)

Precaution

Iron Sucrose should be administered with caution in patients with asthma, eczema, other atopic allergies or allergic reaction to other parenteral Iron preparations, low binding capacity and/or folic acid deficiency, liver dysfunction, acute or chronic infection. Baseline tests: Ensure Hgb, Hct, serum ferritin and transferrin saturation is determined before starting therapy and periodically during treatment. Note that serum Iron levels may be reliably obtained 48 hours after IV dosing. Blood Pressure: Monitor Blood Pressure during infusion. If hypotension occurs, slow the rate of infusion. If hypotension continues, discontinue infusion and be prepared to treat appropriately. Discontinue oral Iron preparations before administering parenteral Iron products. Co-administration of parenteral Iron preparations may reduce absorption of oral Iron.The dose will be in terms of elemental Iron. For IV administration only. Not for intradermal, subcutaneous, IM, or intra-arterial administration. Medication is administered 1 to 3 times/ week. Do not administer more than 3 times/week. Discard any unused diluted solution. Do not save unused solution for future use. Do not administer if particulate matter or discoloration noted. Lactation: Not known if excreted in breast milk, use caution

Indication

Iron deficiency anemia in pregnancy and in non-dialysis dependent chronic kidney disease (CKD) patients, hemodialysis dependent CKD patients or peritoneal dialysis CKD patients.

Contra indication

The use of Iron Sucrose is contraindicated in patients with evidence of Iron overload e.g. Haemochromatosis, thalassemia or haemosiderosis and in patients with known hypersensitivity to Iron preparations or any components preparation, in patients with anemia not caused by Iron deficiency.

Side Effect

>10% Hypotension (36%),Muscle cramps (23%),Headache,Nausea 1-10% Dizziness,Fatigue,Arthralgia,Back pain,Hypertension,Fluid overload,Peripheral edema,Cough,Vomiting,Diarrhea,Constipation,Pruritus Frequency Not Defined Potentially fatal anaphylaxis (rare)

Pregnancy Category ID

2

Mode of Action

Iron: Essential component in the formation of hemoglobin; adequate amounts of iron are necessary for effective erythropoiesis; also serves as a cofactor of several essential enzymes, including cytochromes that are involved in electron transport. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin.

Interaction

May reduce the serum levels of cefdinir; stools may appear red due to the formation of an insoluble iron-cefdinir complex. May reduce the serum levels of eltrombopag. May decrease absorption of phosphate supplements. Concurrent use with trientine may result in reduction of serum levels of iron sucrose and/or trientine. Potentially Fatal: Dimercaprol may increase the nephrotoxic effect of iron salts when used concurrently.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration