FELDENE 20mg Price

Overview

Welcome to Dwaey, specifically on FELDENE 20mg Rectal Suppositories page.
This medicine contains an important and useful components, as it consists of Piroxicam.
FELDENE 20mg is available in the market in concentration 20mg/Suppository and in the form of Rectal Suppositories.

PFIZER GmbH is the producer of FELDENE 20mg and it is imported from GERMANY, The most popular alternatives of FELDENE 20mg are listed downward .

Mode Of Action

Piroxicam is a NSAID, belonging to the oxicam group. It inhibits prostaglandin synthesis, reduces fever by acting on the heat-regulating center of the hypothalamus, inhibits platelet-aggregating substance thromboxane A2 and reduces pain receptor sensitivity. It also exerts anti-inflammatory effect by lysosomal stabilisation, kinin and leukotriene production, alteration of chemotactic factors and neutrophil activation inhibition.

Indication

• Acute gout
• Rheumatic disorders
• Postoperative pain
• Acute musculoskeletal conditions
• Juvenile idiopathic arthritis

Precaution

Patient w/ known CV disease or risk factors for CV disease, fluid retention or heart failure, cerebrovascular disease, uncontrolled HTN, asthma. Elderly. Renal and hepatic impairment. Pregnancy and lactation. Patient Counselling This drug may cause dizziness, drowsiness, fatigue or visual disturbance, if affected, do not drive or operate machinery. Monitoring Parameters Monitor occult blood loss, Hb, haematocrit, electrolytes, renal and hepatic function; periodic ophthalmologic exams w/ chronic use. Closely monitor BP during initiation and throughout therapy. Lactation: excreted in breast milk; has adverse effect on the nursing infant

Side Effects

• 1-10% Indigestion (3.8-9.5% )
• Upper respiratory infection (up to 8.3% )
• Headache (2.4-8.3% )
• Diarrhea (1.9-7.8% )
• Nausea (2.4-7.2% )
• Abdominal pain (1.9-4.7%)
• Edema (0.6- 4.5%)
• Anemia (up to 4.1% )
• Dizziness (1.1-3.8% )
• Constipation (0.8-2.6% )
• Vomiting
• Fever
• Angina (<2% )
• Congestive heart failure (<2% )
• Hypertension (<2% )
• Myocardial infarction (<2% )
• Gastrointestinal hemorrhage (< 2% )
• Gastrointestinal perforation
• gastrointestinal ulcer (< 2% )
• Inflammatory disorder of digestive tract (<2% )
• Decreased platelet aggregation
• purpuric disorder (<2% )
• Hepatitis (<2% ) <1% Erythema multiforme
• erythroderma
• Stevens-Johnson syndrome
• Toxic epidermal necrolysis
• Jaundice
• liver failure
• Anaphylactoid reaction
• Immune hypersensitivity reaction
• Cerebrovascular accident
• Interstitial nephritis
• renal failure
• Asthma
• bronchospasm
• Angioedema
• Tinnitus
• hearing loss Potentially Fatal: Thrombocytopaenia and acute nephropathy. Toxic epidermal necrolysis and Stevens-Johnson syndrome.

Contra indication

Hypersensitivity or asthma-type reactions to piroxicam, aspirin or other NSAIDs. History or active GI ulceration, bleeding and perforation; history of GI disorders that predispose to bleeding disorders (e.g. ulcerative colitis, Crohn's disease, GI cancers or diverticulitis). Treatment of perioperative pain in the setting of CABG surgery. Concomitant use w/ aspirin, other NSAIDs and anticoagulants.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Pregnancy Category: C, D during third trimester of pregnancy (may cause premature closure of the ductus arteriosus)