Active Substance: Factor IX -.
Overview
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This medicine contains an important and useful components, as it consists of
Factor IX -is available in the market in concentration
Factor IX Complex
Caution when used in patients at risk of thromboembolism or disseminated intravascular coagulation. May cause increased risk of intravascular coagulation and thrombosis in patients with hepatic impairment. Risk of viral infection transmission as factor IX complex is a plasma-derived product. Vaccination against hepatitis A and B are recommended in haemophilic patients. Safety and efficacy have not been demostrated in patients < 16 yr. Pregnancy. Lactation: Unknown if distributed in human breast milk
Haemophilia B
Hypersensitivity to mouse or hamster protein.
Nausea and vomiting, headache, and flushing particularly after rapid infusion. Hypersensitivity reactions such as chills and urticaria. Formation of circulating antibodies inhibiting Factor IX Potentially Fatal: Severe allergic reactions.
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Factor IX is used as replacement therapy in patients with haemophilia B whereby there is a genetic deficiency of factor IX.
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