EUDYNA 0.05% Price

Overview

Welcome to Dwaey, specifically on EUDYNA 0.05% Cream page.
This medicine contains an important and useful components, as it consists of Tretinoin.
EUDYNA 0.05% is available in the market in concentration 0.5mg/g and in the form of Cream.

NORDMARK is the producer of EUDYNA 0.05% and it is imported from UK, The most popular alternatives of EUDYNA 0.05% are listed downward .

Mode Of Action

Tretinoin is a trans-retinoic acid form of vitimin A. It stimulates mitosis and turnover of follicular epithelial cells and reduce their cohesiveness. This facilitates extrusion of existing comedones and prevents formation of new comedone. It also exhibits thinning effect on the stratum corneum. In acute promyelocytic leukaemia, it induces cellular differentiation and decreases proliferations.

Indication

• Acute promyelocytic leukaemia

Precaution

Children, hepatic or renal impairment. Reduce dose if intractable headache occurs. Discontinue temporarily if LFT exceed 5 times upper limit of normal. Monitor closely for leukocytosis or respiratory compromise. Monitor haematologic profile, coagulation parameters, LFT, serum triglyceride and cholesterol concentrations regularly. Lactation: Unknown if excreted in breast milk; do not breast-feed, because of potential for serious adverse reactions in infant

Side Effects

• >10% Headache (86%)
• Fever (83%)
• Bone pain (77%)
• Dry mucous membranes (77%)
• Malaise (67%)
• URI (63%)
• Shivering (60%)
• Dyspnea (60%)
• Hemorrhage (60%)
• Elevated liver function tests (50-60%)
• Hyperlipidemia (60%).Infections (58%)
• Nausea and vomiting (57%)
• Rash (54%)
• Peripheral edema (52%)
• Leukocytosis (40%)
• Pain (37%)
• Abdominal pain (31%)
• DIC (26%)
• Respiratory insufficiency (26%)
• Mucositis (26%)
• GI disorder (26%)
• Retinoic acid-APL syndrome (25%)
• Ear ache (23%)
• Diarrhea (23%)
• Pleural effusion (20%)
• Dizziness (20%)
• Pruritus (20%)
• Sweating (20%)
• Anxiety (17%)
• Paresthesia (17%)
• Constipation (17%)
• Vision changes (17%)
• Dyspepsia (14%)
• Depression(14%)
• Insomnia (14%)
• Alopecia (14%)
• Skin changes (14%)
• Confusion (11%)
• Abdominal distention (11%)
• Renal insufficiency (11%) 1-10% (selected) Cardiac failure
• Pseudotumor cerebri
• Ulcer Potentially Fatal: Retinoic acid syndrome
• cardiac arrthythmia
• disseminated intravascular coagulation
• blood dyscrasias
• cardiac arrest
• cerebral haemorrhage.

Contra indication

Hypersensitivity to retinoids. Application to eczematous, sunburnt or abraded skin. Pregnancy, lactation.

Pregnancy and lactation

Pregnancy category: D

There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.