ESTRADERM TTS 100 Price

Overview

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This medicine contains an important and useful components, as it consists of
Estradiolis available in the market in concentration

Name

Estradiol

Precaution

Conditions exacerbated by fluid retention; hypercalcaemia, cerebrovascular diorders, coronary artery disease, gall bladder diseases; lipid effects; familial defects of lipoprotein metabolism. May increase BP, risk of venous thromboembolism, breast cancer, benign hepatic adenoma, endometrial cancer and size of preexisting uterine leiomyomata. Dosage should be reduced in hepatic impairment. Lactation. Child. Lactation: Drug enters breast milk; use with caution

Indication

Moderate to severe vasomotor symptoms associated with menopause, Prophylaxis of osteoporosis in postmenopausal women, Hypogonadism, Atrophic vaginitis

Contra indication

Hypersensitivity; undiagnosed vag bleeding; thrombophloebitis or thromboembolic disorders; breast carcinoma except in selected patients being treated for metastatic disease; oestrogen-dependent tumor; porphyria; pregnancy.

Side Effect

Anxiety,Abdominal cramping,Amenorrhea,Bloating,Breakthrough bleeding,Breast enlargement,Breast tenderness,Delayed ejaculation,Depression,Dry mouth,Headache,Hypertension,Impotency,Influenza,Leukorrhea,Melasma,Muscle cramps,Nausea,Nervousness,Peripheral edema,Polydipsia,Pruritus,Rash,Swelling,Spotting,Syncope,Toothache,Vaginal discomfort, vaginal erosion, vaginal ulceration, adherence of the vaginal ring to the vaginal wall (Estring),Vomiting,Weight changes

Pregnancy Category ID

5

Mode of Action

Estradiol is a naturally occurring oestrogen. Oestrogens are responsible for the development and maintenance of the female reproductive system and secondary sexual characteristics. They modulate the pituitary secretion of gonadotrophins, LH and FSH through a negative feedback system.

Interaction

CYP1A2 and CYP3A4 inducers e.g. aminoglutethimide, carbamazepine, phenobarbital, and rifampin may decrease the effects of estradiol. May enhance the effects of hydrocortisone and prednisolone when used together.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration