EPIVIR 150mg Price

Overview

Welcome to Dwaey, specifically on EPIVIR 150mg page.
This medicine contains an important and useful components, as it consists of
Lamivudineis available in the market in concentration

Name

Lamivudine

Precaution

Discontinue use if there is rapid increase in aminotransferase levels, progressive hepatomegaly, or metabolic or lactic acidosis of unknown origin. Discontinue use if clinical signs, symptoms or lab abnormalities suggestive of pancreatitis develop. Hepatomegaly or other risk factors for hepatic impairment. Monitor hepatic function in chronic hepatitis B patients. Exclude HIV infection prior to hepatitis B therapy. Renal impairment. Pregnancy.

Indication

HIV infection, Chronic hepatitis B

Contra indication

Hypersensitivity. Lactation.

Side Effect

>10% Cough,Diarrhea,Fatigue & malaise,Fever (peds),Headache,Musculoskeletal pain,Nausea,Nervous system neuropathy,Pancreatitis,Peripheral neuropathy,Nasal S/S,Vomiting 1-10% Abdominal cramps, abdominal pain,Anorexia &/or decr appetite,Arthralgia,Chills,Depression,Dizziness,Dyspepsia,Insomnia,Myalgia,Rash,Thrombocytopenia,Creatine phosphokinase increased Frequency Not Defined Body fat redistribution,Elevated amylase,Neutropenia,Hepatitis B exacerbation Potentially Fatal: Lactic acidosis associated with severe hepatomegaly and hepatic steatosis.

Pregnancy Category ID

3

Mode of Action

Lamivudine, a nucleoside analogue, is phosphorylated in the body to the active triphosphate form. In the active form, it inhibits hepatitis B virus polymerase and HIV reverse transcriptase enzymes.

Interaction

Renal excretion may be inhibited by high doses of trimethoprim (co-trimoxazole). May antagonise the antiviral action of zalcitabine.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration