ELIDEL 1% _ Price

Overview

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This medicine contains an important and useful components, as it consists of
Pimecrolimusis available in the market in concentration

Name

Pimecrolimus 1% Topical

Precaution

Avoid use in areas affected by active, cutaneous viral infections. Avoid contact with the eyes and mucous membranes. Immunosuppression may increase risk of lymphoma and other malignancies. Limit exposure to sunlight or other UV light. Mild to moderate sensation of warmth and/or burning may occur at the treatment site within 1-5 days of initiation. Safety of usage beyond 1 yr is not established. Renal or hepatic impairment. Monitor renal, hepatic, cardiac and visual functions, BP, serum glucose and electrolytes regularly. Pregnancy, lactation. Lactation: not known whether distributed in breast milk; may cause unwanted effects in nursing babies

Indication

Atopic dermatitis, Eczema

Contra indication

Hypersensitivity; children <2 yr; immunocompromised patients. Patients with Netherton's syndrome.

Side Effect

>10% Burning sensation (2-26%),Headache (7-25%),Fever (1-13%),Nasopharyngitis (8-27%),Cough (2-16%),Bronchitis (<11%),Upper respiratory tract infection (4-19%) <1% Basal cell carcinoma of skin,Malignant melanoma,Squamous cell carcinoma,Malignant lymphoma,Septic arthritis,Skin discoloration,Eczema,Flushing,Ocular irritation Frequency Not Defined Skin infection,Rash,Application site pain,Paraesthesia,Desquamation,Dryness

Pregnancy Category ID

3

Mode of Action

Pimecrolimus is a macrolactam and is a derivative of ascomycin. It is an immunosuppressant which inhibits the activation of T-cells and prevents the release of inflammatory mediators from mast cells. It is used for the short term or intermittent long term treatment for mild to moderate atopic eczema.

Interaction

Inhibitors of cytochrome P450 3A4 isoenzyme in patients with widespread and/or erythrodermic disease. Potentially Fatal: Increased risk of infections when used with live vaccines.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration