EFLUARIL 50mg/ml Price in UAE

Overview

Welcome to Dwaey, specifically on EFLUARIL 50mg/ml page.
This medicine contains an important and useful components, as it consists of
Fluorouracilis available in the market in concentration

Name

5-Fluorouracil (5-FU)

Precaution

Regular monitoring of blood counts. History of heart disease, hepatic or renal insufficiency, weak or malnourished patients, patients who with history of high-dose pelvic radiation or use of alkylating agents. Patients with widespread metastases to the bone marrow. Lactation: excretion in milk unknown; do not nurse.

Indication

Palliation of malignant neoplasms, Superficial basal cell carcinoma, Oesophageal carcinoma, Cancers of Colon, Breast, Ovary, Liver, Pancreas, Rectum, Stomach

Contra indication

Topical application on mucous membranes, exposure to sunlight, hypersensitivity. Depressed bone marrow function, poor nutritional status, potentially serious infections. Pregnancy and lactation.

Side Effect

1-10% Loss of appetite,Headache,Nausea,Vomiting,Diarrhea,Mucositis,Myelosuppression,Alopecia,Photosensitivity,Hand-foot syndrome,Maculopapular eruption (pruritic) Frequency Not Defined Angina,Coronary arteriosclerosis,Thrombophlebitis,Darkening of veins,Gastrointestinal ulcer,Increased alkaline phosphatase,Increased LFTs,Hyperbilirubinemia,Hypercholesterolemia (increased LDH),Anaphylaxis,Nystagmus,Ophthalmic findings Potentially Fatal: Central neurotoxicity, myocardial ischaemia.

Pregnancy Category ID

Mode of Action

Fluorouracil interferes with DNA synthesis by blocking the conversion of deoxyuridylic acid to thymidylic acid. It also interferes with RNA synthesis. This results in an unbalanced growth of the cells. Fluorouracil exerts greater effect on rapidly growing cells as they take up the drug at a faster rate.

Interaction

May increase warfarin effects. May reduce response to vaccines; possibility of generalized infection with live vaccines. Action may be modified by allopurinol. Leucovorin calcium may enhance the toxicity of fluorouracil.