DOLURIC 80mg Price
Active Substance: Febuxostat.
Overview
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This medicine contains an important and useful components, as it consists of
Febuxostatis available in the market in concentration
Name
Febuxostat
Precaution
Gout Flare: An increase in gout flares is frequently observed during initiation of anti-hyperuricemic agents, including Febustat. If a gout flare occurs during treatment, Febustat need not be discontinued. Prophylactic therapy (i.e., non-steroidal anti-inflammatory drug (NSAID) or colchicine upon initiation of treatment) may be beneficial for up to six months. Lactation: Unknown whether drug is excreted into breast milk; use with caution
Indication
Gout, Hyperuricemia
Contra indication
Patients being treated with azathioprine, mercaptopurine, or theophylline.
Side Effect
>1% Arthralgia,Elevated liver function test (LFT) results,Liver function abnormalities,Nausea,Rash
Pregnancy Category ID
3
Mode of Action
Febuxostat selectively inhibits xanthine oxidase, the enzyme that catalyses the conversion of hypoxanthine to xanthine to uric acid, thereby decreasing serum concentrations of uric acid.
Interaction
May increase plasma conc of mercaptopurine, azathioprine. Alteration of metabolism of xanthine oxidase substrate drugs (eg theophylline).
Pregnancy Category Note
Information not available
Adult Dose
Child Dose
Renal Dose
Administration
