DIROGIT 500mg price in UAE

Overview

Welcome to Dwaey, specifically on DIROGIT 500mg Tablets/Film-coated page.
This medicine contains an important and useful components, as it consists of Capecitabine.
DIROGIT 500mg is available in the market in concentration 500mg/Tablet and in the form of Tablets/Film-coated.

HIKMA PHARMACEUTICALS is the producer of DIROGIT 500mg and it is imported from JORDAN, The most popular alternatives of DIROGIT 500mg are listed downward .

Mode Of Action

Capecitabine is a prodrug that is converted to fluorouracil following oral administration, which in turn inhibits thymidylate synthetase, blocking the methylation of deoxyuridylic acid to thymidylic acid, interfering with DNA, and to a lesser degree, RNA synthesis.

Indication

Breast cancer
Colorectal cancer
Gastric cancer
Oesophageal cancer

Precaution

Hepatic dysfunction, bone marrow suppression, poor nutritional status, warfarin therapy. Child, elderly, prior extensive pelvic radiation or alkylating therapy. Moderate renal impairment; CBC with differential; monitor hepatic and renal function. Discontinue use if intractable diarrhoea, stomatitis, bone marrow suppression or MI develops.

Side Effects

10% Diarrhea
Nausea
Anemia
Lymphopenia
Hand and foot syndrome
Edema
Fatigue
Fever
Headache
Pain
Paresthesia
Alopecia
Dermatitis
Abdominal pain
Anorexia
Appetite decreased
Constipation
Dyspepsia
Stomatitis
Vomiting
Neutropenia
Thrombocytopenia
Dyspnea
Bilirubin increased
Eye irritation 1-10% Chest pain
Dermatitis
Pruritus
Rash
Dizziness
Headache
Weakness
Dehydration
Dry mouth
Dyspepsia
Taste disturbance
Back pain Potentially Fatal: Cardiotoxicity
bone-marrow depression and hyperbilirubinaemia.

Contra indication

History of severe and unexpected reactions to fluoropyrimidine therapy; severe renal impairment; pregnancy, lactation. Hypersensitivity.

Pregnancy and lactation

Pregnancy category: D

There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.