DIPHLAG 14mg/ 5ml Price

Overview

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This medicine contains an important and useful components, as it consists of
Diphenhydramine hydrochlorideis available in the market in concentration

Name

Diphenhydramine Hydrochloride

Precaution

Epilepsy; elderly; performing tasks which require mental alertness; angle-closure glaucoma; pyroduodenal obstruction; urinary tract obstruction; hyperthyroidism; raised intraocular pressure; CV disease; acute asthma; pregnancy. Lactation: Drug enters breast milk; contraindicated

Indication

Allergic rhinitis, Allergic conditions, Motion sickness, Common cold, Insomnia, Extrapyramidal symptoms

Contra indication

Hypersensitivity ; neonates, lactation.

Side Effect

Chest tightness, extrasystoles, hypotension, palpitations, tachycardia; ataxia, chills, confusion, dizziness, drowsiness, euphoria, excitement, fatigue, headache, insomnia, irritability, nervousness, neuritis, paraesthesia, paradoxical excitation, restlessness, sedation, seizure, vertigo; diaphoresis; menstrual disease; GI disturbances (e.g. anorexia, constipation, diarrhoea); difficulty in micturition, urinary frequency, urinary retention; agranulocytosis, haemolytic anaemia, thrombocytopenia; anaphylactic shock; tremor; blurred vision, diplopia; acute labyrinthitis, tinnitus; constriction of pharynx, nasal congestion, thickening of bronchial secretions, wheezing;

Pregnancy Category ID

2

Mode of Action

Diphenhydramine blocks histamine H1-receptors on effector cells of the GI tract, blood vessels and respiratory tract. It also causes sedation and has some anticholinergic action.

Interaction

Masks ototoxicity produced by aminoglycosides. Increases gastric degradation of levodopa and decreases its absorption by reduction of gastric emptying. Antagonises therapeutic effects of cholinergic agents e.g. tacrine, donezepil and neuroleptics. Valerian, St. John's wort, Kava Kava and gotu kola may increase CNS depression. Potentially Fatal: Potentiates CNS depression with alcohol, barbiturates, analgesics, sedatives and neuroleptics. Additive antimuscarinic action with MAOIs, atropine and TCAs.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration