COPARA 0.266mg Price

Overview

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This medicine contains an important and useful components, as it consists of
Calcifediol monohydrate is available in the market in concentration

Name

Zinc Sulphate Monohydrate

Precaution

Before starting **Zinc Sulphate Monohydrate**, patients should always consult a healthcare provider to assess if the medication is appropriate for them, particularly in the following circumstances: - **Allergy to Zinc**: Patients who are allergic to **zinc** or any other ingredients in the formulation should avoid using **Zinc Sulphate Monohydrate**. - **Renal Impairment**: In patients with **kidney disease**, especially those with **renal failure**, Zinc Sulphate should be used with caution, as the body may not eliminate zinc effectively, leading to **zinc toxicity**. Kidney function should be monitored closely. - **Pregnancy**: Zinc is an essential mineral during pregnancy, but the dosage should be controlled. Excessive zinc intake can interfere with **copper absorption** and can lead to **copper deficiency**, which could affect fetal development. It is important to follow a healthcare provider’s guidance regarding dosage. - **Breastfeeding**: Zinc is excreted in breast milk, and while the mineral is essential during breastfeeding, excessive intake should be avoided. The recommended daily intake should not be exceeded without medical advice. - **Iron Deficiency**: High doses of **Zinc Sulphate** may impair the absorption of **iron**. If both zinc and iron supplementation are required, they should be taken at different times of the day to avoid interference with absorption. - **Diarrhea**: Zinc Sulphate can occasionally cause **gastrointestinal irritation** like nausea or diarrhea. Patients with pre-existing gastrointestinal conditions should discuss use with their healthcare provider.

Indication

**Zinc Sulphate Monohydrate** is primarily used for: - **Zinc Deficiency**: Zinc is essential for various bodily functions, including immune system support, wound healing, protein synthesis, and DNA synthesis. Zinc Sulphate is commonly prescribed to **treat or prevent zinc deficiency** in individuals who cannot meet their zinc requirements through diet alone. - **Diarrhea**: Zinc supplementation is recommended for **children with acute diarrhea**, as it can reduce the severity and duration of the condition. The World Health Organization (WHO) recommends zinc as part of the treatment for diarrhea in children. - **Wound Healing**: Zinc plays a vital role in the repair and regeneration of tissues. Zinc Sulphate is sometimes used in cases where **wound healing** is delayed due to zinc deficiency. - **Acne**: Zinc has **anti-inflammatory** properties and may be used as an adjunct treatment for **acne vulgaris** in certain cases, as it can help to reduce inflammation and improve skin condition. - **Immune System Support**: Zinc is important for the functioning of the immune system. It is often included in dietary supplements to **boost immunity**, especially during cold and flu seasons.

Contra indication

**Zinc Sulphate Monohydrate** should not be used in the following situations: - **Hypersensitivity to Zinc**: Individuals with an allergy to **zinc** or any of the excipients in the formulation should avoid this supplement. - **Wilson's Disease**: People with **Wilson's disease**, a genetic disorder that results in **excess copper buildup** in the body, should avoid zinc supplementation as it may exacerbate the accumulation of copper. - **Severe Renal Impairment**: Zinc Sulphate should be avoided in patients with severe **renal impairment** or **end-stage kidney disease**, as their ability to excrete zinc may be compromised, leading to toxicity. - **Excessive Zinc Intake**: Long-term or high doses of zinc can lead to **zinc toxicity**, with symptoms including nausea, vomiting, and **copper deficiency**. Therefore, it should not be used in excess without professional supervision.

Side Effect

Common and severe side effects associated with **Zinc Sulphate Monohydrate** include: - **Common Side Effects**: - **Nausea and Vomiting**: Zinc supplementation can cause gastrointestinal discomfort, especially when taken in high doses or on an empty stomach. - **Stomach Upset**: Many users report symptoms such as **abdominal pain**, **cramps**, or **diarrhea**, particularly at higher doses. - **Metallic Taste**: A common side effect is a **metallic taste** in the mouth, which can be unpleasant but is typically transient. - **Severe Side Effects**: - **Zinc Toxicity**: High doses of zinc can lead to **toxicity**, with symptoms such as **nausea**, **vomiting**, **diarrhea**, and **headache**. Chronic toxicity may also lead to **copper deficiency**, which can cause **anemia**, **neurological problems**, and **bone marrow suppression**. - **Liver Damage**: Although rare, excessive zinc intake can lead to liver damage. Patients should be aware of signs such as **yellowing of the skin or eyes (jaundice)**, which may indicate liver problems. - **Immune System Impairment**: Paradoxically, excessive zinc intake can impair immune function, reducing the body’s ability to fight infections.

Pregnancy Category ID

0

Mode of Action

**Zinc Sulphate Monohydrate** acts as a **dietary supplement** to address zinc deficiency. Zinc plays a vital role in over 300 enzymatic processes in the body, making it essential for: - **Immune Function**: Zinc supports the immune system by influencing the production and function of white blood cells, which are critical for immune response. - **Protein Synthesis and Cell Division**: Zinc is involved in **protein synthesis** and **DNA synthesis**, both of which are critical for growth, tissue repair, and wound healing. - **Antioxidant Properties**: Zinc also acts as an **antioxidant**, helping to reduce oxidative stress in cells. - **Skin Health**: Zinc is involved in the regulation of **skin cell production** and **repair**, which is important for wound healing and treating conditions like acne.

Interaction

Zinc Sulphate can interact with several medications and substances, including: - **Antibiotics**: Zinc may interfere with the absorption of certain **antibiotics** such as **quinolone antibiotics** (e.g., **ciprofloxacin**) and **tetracycline antibiotics** (e.g., **doxycycline**). It is generally recommended to take zinc supplements at least **2 hours apart** from these antibiotics to prevent interference with absorption. - **Iron Supplements**: High doses of **zinc** can reduce the absorption of **iron**, and vice versa. If both supplements are required, they should be taken at different times of the day. - **Copper Deficiency**: Long-term use of zinc in high doses can result in **copper deficiency**, which can lead to **neurological disorders**. Zinc supplements should be used with caution in people with a history of copper deficiency. - **Diuretics**: Certain **diuretics** (e.g., **thiazide diuretics**) can increase the excretion of zinc, leading to a **zinc deficiency** over time. Regular monitoring of zinc levels is recommended for patients on diuretics. - **Penicillamine**: This **chelating agent** used in treating **Wilson’s disease** can interact with zinc, reducing its effectiveness. Patients should avoid simultaneous use without medical guidance.

Pregnancy Category Note

Information not available

Adult Dose

The typical dose of **Zinc Sulphate Monohydrate** for adults is: - **For Zinc Deficiency**: The recommended daily dose is typically **25-50 mg** of zinc, usually given as a single dose or divided doses. Higher doses may be used in cases of severe deficiency, but it should not exceed **200 mg per day** unless directed by a healthcare provider. - **For Wound Healing and Acne**: A dose of **30-50 mg daily** may be used, depending on the severity of the condition. - **For Diarrhea in Children**: Zinc supplementation for diarrhea is usually in the form of **20 mg daily** for **children over 6 months** for 10-14 days.

Child Dose

The dose of **Zinc Sulphate Monohydrate** in children varies based on the condition being treated: - **For Zinc Deficiency**: - **Infants (under 6 months)**: **2-5 mg daily**. - **Children (6 months to 4 years)**: **10 mg daily**. - **Children (5-12 years)**: **20 mg daily**. - **Adolescents (13 years and older)**: **25 mg daily**. - **For Diarrhea**: For children with diarrhea, the World Health Organization (WHO) recommends **20 mg daily** for children over 6 months of age for **10-14 days**. --- As with all supplements, **consulting a healthcare provider** is essential before starting **Zinc Sulphate Monohydrate** to ensure appropriate use and avoid potential side effects or interactions. Regular monitoring of zinc levels and other parameters may be needed, particularly in individuals with pre-existing health conditions or those on multiple medications.

Renal Dose

In patients with **renal impairment**, especially those with **severe kidney dysfunction**, Zinc Sulphate should be used with caution. The kidney’s ability to excrete zinc may be impaired, leading to **zinc toxicity**. Dose reductions and close monitoring of zinc levels are necessary in patients with renal dysfunction.

Administration

Information not available