COLMACYN 0.5mg price in UAE

Overview

Welcome to Dwaey, specifically on COLMACYN 0.5mg Tablets/Film-coated page.
This medicine contains an important and useful components, as it consists of Colchicine.
COLMACYN 0.5mg is available in the market in concentration 0.5mg/Tablet and in the form of Tablets/Film-coated.

MACLEODS PHARMACEUTICALS LTD. is the producer of COLMACYN 0.5mg and it is imported from INDIA, The most popular alternatives of COLMACYN 0.5mg are listed downward .

Mode Of Action

Colchicine, a phenanthrene derivative, exerts its effect by reducing the inflammatory response to the deposited urate crystals and also by diminishing phagocytosis in joints. It inhibits lactic acid production by leucocytes, thereby interrupting urate deposition and inflammatory response that sustains the acute gout attack.

Indication

Acute gout
Familial Mediterranean Fever
Behcet's disease
Gouty arthritis

Precaution

Elderly; GI disease. Cardiac, renal and hepatic impairment; prolonged therapy not recommended; lactation. Lactation: Drug enters breast milk; use with caution (American Academy of Pediatrics Committee states that drug is "compatible" with nursing)

Side Effects

>10% Gastrointestinal (GI) effects (eg
diarrhea
nausea
cramping
abdominal pain
vomiting) (26-77%) 1-10% Fatigue (1-4%)
Gout (0-4%)
Pharyngolaryngeal pain (2-3%)
Headache (1-2%)

Contra indication

Hypersensitivity; blood dyscrasias, severe renal impairment, pregnancy, debilitated patients; SC/IM admin.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Reversible malabsorption of vitamin B12 may occur because of ileal mucosal function alteration. Response to CNS depressants and sympathomimetics may increase when used concurrently with colchicine. Increased risk of myopathy when used concurrently with simvastatin. Potentially Fatal: With ciclosporin, increased risk of nephrotoxicity and myotoxicity. Risk of colchicine toxicity when used with macrolides.