CLOBATE 0.05% Price

Overview

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This medicine contains an important and useful components, as it consists of
Clobetasone butyrateis available in the market in concentration

Name

Clobetasone butyrate 0.05% Topical

Precaution

May be absorbed in sufficient amounts to cause systemic effects when applied topically to large areas, broken skin or under occlusive dressings. Peptic ulcer, osteoporosis, psychoses or severe psychoneuroses. Not to be used indiscriminately for pruritus. CHF or hypertension. Diabetes mellitus, epilepsy, glaucoma, infectious diseases, ocular herpes simplex, chronic renal failure and uraemia. Active or doubtfully quiescent tuberculosis. Local treatment of eye disorders. Elderly. Prolonged use on the face.

Indication

Inflammatory skin disorders. All types of eczema & dermatitis, including atopic eczema, photodermatitis, otitis externa, primary irritant & allergic dermatitis (napkin rash), prurigo nodularis, seborrhoeic dermatitis & insect bite reactions.

Contra indication

Pregnancy (in high doses). Presence of acute infections. Treatment of rosacea; leg ulcers; acne vulgaris; widespread plaque psoriasis. Child <1 yr.

Side Effect

Local atrophic changes; pigmentation changes & hypertrichosis. Increased liability to infection. Infections may be masked. Acute adrenal insufficiency. Growth retardation in child. Cushingoid symptoms. Amenorrhoea, hyperhidrosis, skin thinning,

Pregnancy Category ID

3

Mode of Action

Clobetasone butyrate is classed as a moderately potent topical corticosteroid. Corticosteroids decrease inflammation by stabilizing leukocyte lysosomal membranes, preventing release of destructive acid hydrolases from leukocytes; inhibiting macrophage accumulation in inflamed areas; reducing leukocyte adhesion to capillary endothelium; reducing capillary wall permeability and edema formation; decreasing complement components; antagonizing histamine activity and release of kinin from substrates; and reducing fibroblast proliferation, collagen deposition, and subsequent scar tissue formation.

Interaction

Information not available

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration