CLAZ MR Price

Overview

Welcome to Dwaey, specifically on CLAZ MR Tablets/Modified Release page.
This medicine contains an important and useful components, as it consists of Gliclazide.
CLAZ MR is available in the market in concentration 30mg/Tablet and in the form of Tablets/Modified Release.

APOTEX PTY is the producer of CLAZ MR and it is imported from AUSTRALIA, The most popular alternatives of CLAZ MR are listed downward .

Mode Of Action

Gliclazide stimulates insulin secretion from pancreatic beta-cells, reduces insulin uptake and glucose output by the liver, and increases insulin sensitivity at peripheral target sites. It decreases microthrombosis by partial inhibition of platelet aggregation and adhesion, and by restoring fibrinolysis w/ an increase in tissue plasminogen activator (t-PA) activity.

Indication

• Type 2 DM

Precaution

Monitor blood glucose concentration. May require insulin during metabolic stress. Care when transferring from combination therapy. Increased risk of severe hypoglycaemia in elderly, debilitated patients, patients with hepatic or renal impairment. Risk of hypogylcaemia when caloric intake is deficient, after strenuous exercise, when taken with ethanol or when >1 antidiabetic drug is used.

Side Effects

• GI disturbances
• skin reaction
• leucopenia
• thrombocytopenia
• agranulocytosis
• haemolytic anaemia
• cholestatic jaundice
• vomiting
• diarrhoea
• gastritis
• increased transaminases.

Contra indication

Type 1 DM, diabetes complicated with ketoacidosis; hypersensitivity; severe renal and hepatic impairment. Pregnancy and lactation.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks