Active Substance: Ceftibuten (as dihydrate).
Overview
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This medicine contains an important and useful components, as it consists of
Ceftibuten (as dihydrate)is available in the market in concentration
Ceftibuten
Hypersensitivity to penicillins; renal impairment; Porphyria. Monitor renal and haematologic status. Lactation: excretion in milk unknown; use with caution
Respiratory tract infections, Urinary tract infections
Hypersensitivity to cephalosporins.
1-10% Increased BUN (4%),Nausea (4%),Diarrhea (3%),Headache (3%),Increased eosinophils (3%),Decreased hemoglobin (2%),Dyspepsia (2%),Thrombocytosis (2%),Abdominal pain (1%),Dizziness (1%),Increased ALT (1%),Increased bilirubin (1%),Vomiting (1%) <1% Anorexia,Candidiasis,Constipation,Dysuria,Agitation,Fatigue,Insomnia,Irritability,Paresthesia,Rigors,Diaper rash,Urticaria,Dry mouth,Dyspnea,Nasal congestion,Increased transaminases,Increased creatinine,Leukopenia Potentially Fatal: Pseudomembranous colitis.
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Ceftibuten inhibits bacterial cell wall synthesis. It is stable to hydrolysis by many beta-lactamases and has greater activity than 1st or 2nd generation cephalosporins against gm-ve bacteria. It is less active in vitro than cefexime against S. pneumoniae.
Enhanced nephrotoxicity of aminoglycosides. Increased serum concentration w/ probenecid. Decreased serum concentration w/ zinc salts.
Information not available