Active Substance: Clotrimazole.
Overview
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This medicine contains an important and useful components, as it consists of
Clotrimazoleis available in the market in concentration
Clotrimazole 1% Topical
Avoid contact with eyes upon topical application. Childn <3 yrs. Pregnancy, lactation.If local intolerance develops, consider withdrawal of the medicine and institution of appropriate therapy. Lactation: Excretion in milk unknown; use with caution
Skin and nail fungal infections, Tinea pedis, Tinea cruris, Tinea corporis, Candidiasis, Pityriasis versicolor
Hypersensitivity.
Elevated serum AST (SGOT) concentrations (15%) Topical: Erythema, stinging, irritation; hypersensitivity reactions; contact dermatitis. Edema, Pruritus, Burning, Stinging, Peeling, Urticaria, Skin fissures
2
Clotrimazole is a broad-spectrum antifungal which binds to phospholipids in the cell membrane altering cell wall permeability causing a loss in essential intracellular elements.
Antagonism with polyene antibiotics.
Pregnancy category B during 2nd and 3rd trimester; safety in 1st trimester not established